摘要
A tunable pulsed laser induced photoacoustic （PA） measurement set-up is established in the forward mode to monitor in vitro glucose concentration. A series of experiments are investigated to verify the feasibility of this set-up and scheme. Peak-to-peak values （PPVs） of several glucose aqueous solutions are recorded and averaged 512 times at each wavelength. Experimental results demonstrate that the time-resolved PA profile of glucose solutions has a good agreement with the PA theories. The characteristic wavelengths of glucose solution are determined via differential method. The root-mean-square error （RMSE） of predicted concentration reaches 3.15 mg/dl at the optimum wavelength of 1 510 nm via least square （LS） fitting algorithm.
A tunable pulsed laser induced photoacoustic （PA） measurement set-up is established in the forward mode to monitor in vitro glucose concentration. A series of experiments are investigated to verify the feasibility of this set-up and scheme. Peak-to-peak values （PPVs） of several glucose aqueous solutions are recorded and averaged 512 times at each wavelength. Experimental results demonstrate that the time-resolved PA profile of glucose solutions has a good agreement with the PA theories. The characteristic wavelengths of glucose solution are determined via differential method. The root-mean-square error （RMSE） of predicted concentration reaches 3.15 mg/dl at the optimum wavelength of 1 510 nm via least square （LS） fitting algorithm.
基金
This work was supported by the National Natural Science Foundation of China （No. 61068002）, the Natural Science Foundation of Jiangxi Province （No. 20114BAB215047）, the Science and Technology Pillar Program of Jiangxi Province （No. 20132BBGT0103） and the Scientific Research Foundation of Jiangxi Provincial Education Bureau （No. GJJ12594）.
