摘要
目的分析恶性肿瘤患者^125I放射性粒子植入后对病区护理人员外周血象的影响并探讨相关防护研究。方法将2002--2012年间中山大学肿瘤防治中心^125I放射性粒子植入后患者的护理人员作为实验组；随机抽取同一时段中山大学肿瘤防治中心未接触^125I放射性粒子植入术患者的护理人员作为对照组，分别抽取两组血常规，并将白细胞、血红蛋白浓度及血小板计数进行比较分析。另外，随机采集30例接受粒子植入术患者，于术后当天使用1射线探测仪在距离患者体表即皮肤手术穿刺点的横截面体表O、15、30、50、100em处从不同角度探测1射线剂量并计算平均值。结果实验组与对照组的白细胞（×10^9／L）、血红蛋白（g／L）浓度及血小板计数（×10^9／L）的异常率差异无统计学意义（7．1±1．7比6．8±2．0，132±11比136±11，236±57比242±61）。在无屏蔽时，距离患者手术穿刺点体表50om所测得的放射剂量[（12．7±4．3）μSv／h]接近天然本底剂量（10．2～10．8μSv／h）。采用0．125mmPb橡胶布屏蔽防护后，零距离处放射剂量[（11．2±3．1）μSv／h]接近天然本底剂量。结论采取相应的防护措施后，^125I放射性粒子植入后对病区护理人员的外周血象无明显影响。
Objective To analyze the blood picture changes of the ward nurses who nurse the patients received^125I seeds implantation. Methods 32 ward nurses who nurse the patients for ^125I seeds implantation were involved in the experimental group, the control group included 32 ward nurses from the medical oncology never exposed to ^125I seeds. The WBC count, hemoglobin concentration and platelet counts from the two groups were analyzed statistically, respectively. 30 patients received 125I seeds implantation were selected randomly and γ-ray dose from the unshielded group and lead rubber cloth covering group was detected at a distance of 0, 15, 30, 50, 100 cm from patient body surface and at different angles. Results No significant statistical difference was found between the two groups of WBC count, hemoglobin concentration and platelet count（7. 1 ＋ 1.7 vs 6. 8 ± 2.0,132 ± 11 vs 136 ± 11,236 ± 57 vs 242 ± 61 ）. The measured radiation dose was close to the natural background dose（ 10. 2 - 10. 8 μSv/h） at a distance of 50 cm from the body surface [ （ 12. 7 ± 4. 3 ） μSv/h] and the same as after 0. 125 mm lead equivalent （Pb） rubber cloth shield protection [ （ 11.2 ± 3.1 ）μSv/h 1. Conclusion Interstitial ^125Iseed implantation is safe on the blood picture of the ward nurses after taking appropriate protective measures.
出处
《中华医学杂志》
CAS
CSCD
北大核心
2013年第41期3269-3271,共3页
National Medical Journal of China
关键词
碘同位素
护理人员
辐射防护
Iodine isotopes
Nursing staff
Radiation protection
