2Thompson SJ,Koszdin K,bernards CM.Opiate-induced analgesia is increased and prolonged in mice lacking P-glycoprotein.Anesthesiology,2000,92:1392-1399. 被引量:1
3Schinkel AH,Wagenaar E,van Deemter L,et al.Absence of the mdrla P-glycoprotein in mice affects tissue distribution and pharmacokinetics of dexamethasone,digoxin,and cyclosporin A.J Clin Invest,1995,96:1698-1705. 被引量:1
4Xie R,Hammarlund U M, Boer AG,et al.The role of P-glycoprotein in blood-brain barrier transport of morphine:transcortical microdialysis studies in mdrla(-/-)and mdrla (+/+) mice.Br J Pharmacol,1999,128:563-568. 被引量:1
5Letrent SP,Polli JW,Humphreys JE,et al.P-glycoprotein-mediated transport of morphine in brain capillary endothelial cells.Biochem Pharmacol,1999,58:951-957. 被引量:1
6Ⅱ enthorn TK,Liu Y,Mahapatro M,et al.Active transport of fentanyl by the blood-brain barrier.J Pharmacol Exp Ther,1999,289:1084-1089. 被引量:1
7Aquilante CL, Letrent SP, Pollack GM, et al.Increased brain P-glycoprotein in morphine tolerant rats.Life Sci,2000,66:47-51. 被引量:1
8Lotsch J, Tegeder I, Angst MS, et al. Antinociceptive effects of morphine-6-glucuronide in homozygous MDR1a P-glycoprotein knockout and in wildtype mice in the hotplate test.Life Sci,2000,66:2393-2403. 被引量:1