摘要
目的 调查孕妇妊娠各期的微量元素水平变化,指导临床合理补充微量元素.方法 对2010年10月至2012年6月来遂宁市中心医院妇产科进行孕前保健的育龄妇女（待孕组）325例、孕期保健孕妇（孕妇组）440例和生产的孕妇（产妇组）387例,平均年龄为23.8±3.9岁,其中同一病人三次都采集标本者161例,分别检测铜、锌、钙、镁、铁的含量,以遂宁地区成人微量元素综合参考范围（铁：7.52～11.82 mmol/L; 钙：1.55～2.10 mmol/L; 锌：76.5～170 mmol/L; 镁：1.12～2.06 mmol/L; 铜：11.8～39.3 mmol/L）为正常对照.结果孕妇组微量元素含量明显下降,铁7.07±1.33 mmol/L,锌87.43±18.55 mmol/L,钙1.51±0.19 mmol/L,镁1.17±0.19 mmoL/L;随着孕期增加,临产时血液铁、锌、钙含量进一步降低,铁5.13±1.02 mmol/L,锌64.21±24.38 mmol/L,钙1.35±0.15 mmol/L,铁、锌、钙含量不同时间组相互比较有显著差异（P〈0.01）.161例三期都在医院作了检测的孕妇,随着孕周的增加,血液铁、锌、钙缺乏人数由孕前和早孕期的11例（6.8%）、2例（1.2%）、21例（13.0%）和77例（47.8%）、24例（14.9%）、63例（39.1%）明显增加,临产期为63例（39.1%）、75例（46.6%）、88例（54.6%）,缺乏率变化显著（P 〈 0.01）.结论 孕妇在孕早期就应重视摄取铁元素,在孕中期后可适当补充铁剂,并增加锌和钙的摄入.
Objective To survey the change in blood levels of trace elements in pregnant women in order to guide the clinical micronutri ant supplementation. Methods Three hundred and twenty five women with childbearing age （ prepregnant group） , 440 pregnant women （ pregnant group） and 387 lying - in women （ maternal group） with a mean age of 23.8± 3.9 years old in Department of Obstrics and Gynecology of this hospital during October 2010 to June 2012 were allocated in ths study, among them 161 women were examined for 3 times of these items. The items examined including contents of copper, zinc, calcium, magnesium and iron, the normal range of trace elements in adults in Suining area for reference as follows： iron： 7.52 -11.82 mmol/L; Ca： 155 - 210 mmol/L; zinc： 765 - 170 mmol/L; magnesium： 1.12 -2.06 mmol / L and copper： 11.8 - 39. 3 mmo]/L for normal control. Results The contents of trace elements in pregnant women were decreased compared with nor-mal controls, the blood content of iron was 7.07 ± 1.33 mmol/L, zinc 87.43 ± 18.55 mmol/L, calcium 1.51 ± O. 19 mmol/L, and magnesium 1.17 ± O. 19 mmol/L. Following the increase of duration of pregnancy, blood contents of iron, zinc, and calcium were further reduced, iron was reduced to 5.13 ± 1.02 mmol/L, zinc to 64.21 ±24.38 mmol/L, and Ca to 1.35 ±0.15 mmoL/L, blood contents of iron, zinc and calcium in different time periods had been compared with each other, there was significant difference between them （ P 〈 001 ）. The contents of blood trace el ements in 161 pregnant women in this hospital were detected with increasing gestational age, the numbers of women with defieney in blood iron, zinc and calcium before pregnancy and during early pregnancy were 11 （6.8%）, and 2 （ 1.2% ）, 21 （ 13.0% ） and 77 （47.8%）, 24 （ 14. 9% ） , 63 （39.1%） respectively, the number of women with defiency had been significantly increased during perinantal period, and they were 63 （39.1% ） , 75 （46.6%） and 88 （54.6%） respective
出处
《临床和实验医学杂志》
2013年第19期1568-1569,共2页
Journal of Clinical and Experimental Medicine
关键词
微量元素
育龄妇女
妊娠
Women of childbearing age
Gestation
Trace elements
