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rhEPO联合蔗糖铁治疗27例血液透析患者肾性贫血的临床观察

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摘要 目的观察重组人促红细胞生成素(rhEPO)联合蔗糖铁治疗血液透析患者肾性贫血的临床效果。方法选择在我科住院的维持性血液透析患者56例,随机分为试验组27例和对照组29例,对照组在rhEPO治疗的基础上给予硫酸亚铁口服,试验组在rhEPO治疗的基础上给予蔗糖铁静滴。观察2组治疗前后血红蛋白(Hb)、红细胞压积(Hct)、网织红细胞计数(Ret)、血清铁蛋白(SF)、转铁蛋白饱和度(TSAT)。每月监测丙氨酸转氨酶(ALT)、天冬氨酸转氨酶(AST)、C反应蛋白(CRP)变化。结果试验组在改善患者Hb、Hct、Ret、SF、TSAT方面明显优于对照组,差异有显著性(P<0.05),2组治疗前后ALT、AST、CRP比较无显著差异(P>0.05)。结论 rhEPO联合蔗糖铁治疗血液透析患者肾性贫血效果明显,安全性好。
作者 邹军锋
机构地区 荆州市中医院
出处 《基层医学论坛》 2013年第28期3731-3732,共2页 The Medical Forum
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