摘要
目的:改进非PVC膜软袋大输液生产工艺的六个关键环节,使生产过程平稳、膜袋成型稳定、成品合格率提高。方法:通过加装第二压缩空气缓冲罐、改装颈热合模具、加装离子风嘴、保持灌封间温度恒定、模具冷却水密闭、探索成品最佳灭菌出锅温度等措施改进非PVC膜软袋大输液生产工艺。结果:有效减少了膜袋大输液不溶性微粒含量,避免了继发性膜袋开裂、成品合格率由97.9%提高到99.9%。结论:生产工艺关键环节的改进措施科学有效,可确保非PVC膜软袋大输液生产过程平稳、产品质量优良,在非PVC膜软袋大输液生产行业具有推广和应用价值。
Objective：This paper delivers six key links of non-PVC soft-package infusion production process to smooth production process; to stabilize membrane bag forming; and to improve product quality. Methods：Non-PVC soft-package infusion production process was improved by setting up another compressed air buffer tank ,installing ion wind mouth, maintaining a constant temperature of filling ~ enveloping room and exploring a suitable temperature to open the sterilizer. The welding mold and the using of cooling water were also improved. Resul ts.The insoluble particles content of non-PVC soft-package infusion and the soft-package cracking rate have been reduced effectively. The production percent of pass has increased from 97. 9% to 99. 9% because of these methods. Conclusion.The improvement key links of the production process make sure membrane bag forming stable and producing high quality scientifically and effectively. These methods are worthy of promoting and applying to the industry of non-PVC soft-package infusion.
出处
《黑龙江医药科学》
2013年第5期32-33,共2页
Heilongjiang Medicine and Pharmacy
关键词
非PVC膜软袋
大输液
生产工艺改进
non--PVC soft -- package
infusion
production process improvement
