摘要
对435例2型糖尿病患者的临床资料进行回顾性分析,发现糖尿病肾病患者血清载脂蛋白E水平显著高于无糖尿病肾病者[50.4（40.8,65.9）对46.2（38.6,56.8）mg/L,P〈0.01],高载脂蛋白E组尿白蛋白/肌酐比值明显高于低载脂蛋白E组（P〈0.01）,载脂蛋白E是尿白蛋白/肌酐比值的独立影响因素（β=0.14,P〈0.05）。
This retrospective analysis showed that the level of apolipoprotein E was significantly higher in diabetic nephropathy group compared with normal albuminuria group[50.4（40.8,65.9）vs 46.2（38.6,56.8）mg/L, P〈0.01]. Difference in urinary albumin to creatinine ratio（ACR）among the groups based on the tertile of apolipoprotein E were significant（P〈0.01）. Multiple linear regression analysis demonstrated that apolipoprotein E was independently associated with ACR（β=0.14, P〈0.05）.
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
2013年第10期879-881,共3页
Chinese Journal of Endocrinology and Metabolism
基金
江苏省自然科学基金项目（BK2011471）
江苏大学高级人才启动基金项目（12JDG047）
关键词
糖尿病。肾病
载脂蛋白E
糖尿病
2型
Diabetic nephropathy
Apolipoprotein E
Diabetes mellitus, type 2
