Synthesis, Thermal Stability and Photochemical Properties of DNA Containing Fluorescent Biaryl-Type Nucleoside Surrogates
Synthesis, Thermal Stability and Photochemical Properties of DNA Containing Fluorescent Biaryl-Type Nucleoside Surrogates
摘要
A major goal of research in biotechnology and nanotechnology is to develop assemblies of novel biomaterials that can be used in analytical, industrial, and therapeutic applications. The synthesis of DNA （oligodeoxyribonucleotide） has been described containing the biaryl-type nucleoside surrogates, 6-deamino-2＇-deoxy-6-（l-naphthyl） adenosine （AN） and 6-deamino-2＇-deoxy-6-（1-pyrenyl） adenosine （AP）. It is found that incorporation of multiple ATM or AP residues in the middle of DNA duplexes does not significantly destabilize the duplexes and that the fluorescence intensities of the oligonucleotides containing AN or Ap significantly increases in the duplexes formed.
参考文献22
-
1Malinovskii, V. L.; Wenger, D.; Hfiner, R. Chem. SocRev. 2010, 39, 410. 被引量：1
-
2Ranasinghe, R. T.; Brown, T. Chem. Commun. 2005, 5487. 被引量：1
-
3Teo, Y. N.; Wilson, J. N.; Kool, E. T. J. Am. Chem. Soc. 2009, 131, 3923. 被引量：1
-
4Verhagen, C.; Bryld, T.; Buchalovfi, K.; Wengel, J 2538. 被引量：1
-
5Raunkja:r, M.; Vogel, S.; Eur. J. Org. Chem. 2006. 被引量：1
-
6Kumar, T. S,; Madsen, A. S.; Ostergaard, M. E.; Wengel, J.; Hrdlicka, P. J. J. Org. Chem. 2008, 73, 7060. 被引量：1
-
7Brauns, E. B.; Madaras, M. L.; Coleman, R. S.; Murphy, C. J.; Berg, M. A. d. Am. Chem. Soc. 1999, 121, 11644. 被引量：1
-
8Nakamura, N.; Murakami, Y.; Sasa, K.; Hayashi, H.; Yamana, K. J. Am. Chem. Soc. 2008, 130, 6904. 被引量：1
-
9Kosuge, M.; Kubota, M.; Ono, A. Tetrahedron Lett. 2004, 45, 3945. 被引量：1
-
10Baumstark, D.; Wagenknecht, H. A. Angew. Chem. Int. Ed. 2008, 47, 2612. 被引量：1
-
1杨雪燕,程晓红.DNA自组装纳米技术研究进展[J].云南化工,2013,40(2):16-21. 被引量：3
-
2阎春兰,代金刚,王恒涛,邱裕尧,王茜.土壤中一株产黑色素微生物的分离与鉴定[J].中南民族大学学报（自然科学版）,2014,33(3):44-46. 被引量：4
-
3刘德晔,朱峰,马永建,吉文亮,刘华良.液相色谱-电感耦合等离子质谱和电喷雾电离质谱研究乙二胺二氯合钯与鸟嘌呤脱氧核糖核苷酸反应产物[J].分析化学,2015,43(2):193-198. 被引量：2
-
4唐晓春,张宜萍.关于脱氧核糖核苷酸的问题解答[J].生物学教学,2009,34(8):58-58.
-
5Zhang, YS,Wang, LX,Zhang, LH.O－（1－BENZOTRIAZOLYL）－SULFATE AS ALEAVING GROUP IN SUBSTITUTION OF NUCLEOSIDE[J].Chinese Chemical Letters,1995,6(7):549-552.
-
6苗志伟,付华,冯玉萍,韩波,涂光忠,赵玉芬.Studies on Synthesis and Intramolecular Catalyzed Hydrolysis of Thiophosphoramidate Derivatives of Nucleoside[J].Chinese Journal of Chemistry,2002,20(11):1434-1438.
-
7Li Ren JIN ,Jian Liang YE,Yong XIE,Jiang Hong SHI,Pei Qiang HUANG,Kyeong Eun JUNG,Hong LIM(Department of Chemistry, Xiamen University Xiamen, Fujian 361005Dongbu Advanced Reseach Institute, Daeduck Science Town, Taejon Korea).Asymmetric Synthesis of Polyhydroxy Pyrrolidinonyl Nucleoside Analogues from Tartaric acid[J].Chinese Chemical Letters,1999,10(7):543-546.
-
8Rut Yun GUO,Jun Biao CHANG,Rong Feng CHEN,Jing Xi XIE(Henan Institute of Chemistry. Zhengzhou 450003).Synthesis of Novel Nucleoside: 2'-deoxyuridine-3',5'-di(4, 4'-dimethoxy-5, 6, 5', 6'-dimethylenedioxybipheny1-2-methoxy carbonyl 2'-carboxylate)[J].Chinese Chemical Letters,1999,10(5):341-344.
-
9张宁,张园,张维冰.超高效液相色谱-串联质谱法鉴定与分析乙醛诱导脱氧核糖核苷酸加合物[J].色谱,2016,34(8):757-761. 被引量：1
-
10Guo Chen CHI,Zhong Biao ZHANG,Xiao Hua Xu and Ru Yu CHEN (Insitute of Elemento-Organic Chemistry, State Key Laboratory of Elemento-Organic Chemistry,Nankai University, Tianjin, 300071).Stable Send-ketals of 3',5'-O-(Tetraisopropyldisiloxane-1,3-diyl)-2'-Ketouridine[J].Chinese Chemical Letters,1998,9(11):989-992.
