摘要
目的调查分析研究昆明地区近12 a来大肠癌的临床发病特点及发病趋势,为临床诊治提供参考.方法收集昆明医科大学第一附属医院2001年7月至2012年12月经病理确诊的1 628例大肠癌患者资料.按其发病时间分为2001年至2006年(A组)和2007年至2012年(B组)两个连续时间段进行统计分析.结果 A组与B组比较,B组收治率上升54.4%;大肠癌的发病率在城市由49.2%上升至56.0%,在乡村由50.8%下降至44.0%(P<0.05);大肠癌的发生部位在直肠的比例由74.8%下降至73.9%,P>0.05;在左半结肠的比例由14.8%上升至19%,而右半结肠比例由10.4%下降至7.1%(P<0.05),前后两个连续的时间段在3个部位的变化有统计学意义(P<0.05);大肠癌中诊断为Dukes A期患者比例由13.4%上升至18.8%,Dukes D患者比例由22.3%下降至14.5%(P<0.01).结论该地区大肠癌的发病率总体呈上升趋势;在城市的发病率明显高于乡村;左半结肠癌的比例上升,直肠癌及右半结肠癌的的比例下降;早期患者诊断率上升.
Objective To provide the basis for clinical diagnosis and treatments of colorectal cancer by studying the clinical characteristics and incidence tendency of colorectal cancer in recent 12 years in Kunming. Methods The data of 1628 colorectal cancer patients from 2001 to 2012 in the First Affiliated Hospital of Kunming Medical University were collected. The clinic pathological data of all patients was divided into 2001-2006 （Agroup） and 2007-2012 （B group） two consecutive time periods for statistical analysis according to its time of onset. Results The incidence of colorectal cancer in the city rose from 49.2%to 56.0%, and the incidence of colorectal cancer in rural areas decreased from 50.8%to 44%（ 〈0.05） .The location ratio of colorectal cancer in the rectum decreased from 74.8%to 73.9%, in the left half colon ratio increased from 14.8%to 19%, while the right colon ratio decreased from 10.4% to 7.1% （ 〈 0.05） . The change in the three parts had statistically significant difference between two consecutive time periods. The percentage of colorectal cancer patients in Dukes A stage rose from 13.4% to 18.8%, while the percentage of patients in Dukes D stage decreased from 22.3% to 14.5% （ 〈0.01） . Conclusions The incidence of colorectal cancer in Kunming gradually increases.The morbidity in the city is significantly higher than that in the country. The ratio of left half colon cancer is rising, but the ratio of rectal cancer and right half colon cancer is falling. The early diagnosis rate of colorectal cancer is on the rise.
出处
《昆明医科大学学报》
CAS
2013年第10期84-87,共4页
Journal of Kunming Medical University
基金
国家自然科学基金资助项目(81160245)
关键词
结直肠肿瘤
临床特点
趋势
Colorectal neoplasm
Clinical characteristics
Tendency
