摘要
本文应用复杂度分析方法研究了轻度认知障碍(MCI)老年人在认知任务下的脑电(EEG)活动规律。通过让老年人判断两个图形颜色是否一致的实验,计算他们在此认知活动下EEG的Lempel-Ziv复杂度(LZC),比较MCI和正常老年人的EEG在时间上的变化及空间分布特性。研究发现:在认知活动初期,老年患者的LZC高于正常老年人(P<0.05);患者的LZC EEG复杂度随时间逐渐减小,而正常人基本不变;颜色一致与不一致任务类型下的EEG的LZC之间没有统计学差异;在空间上,MCI和正常对照组有相似的分布规律。
We studied the mechanism of electroencephalography （EEG） in the elderly with mild cognitive impairment （MCI） by analyzing the Lempel-Ziv complexity （LZC） of EEG during a cognitive task. We recorded the EEG simul- taneously when they were asked to judge whether the color of two graphics was matched or not. The results showed that the LZC of EEG in the MCI group was significantly higher than those in the normal control group early in the period of cognitive activities （P〈0.05）. The LZC in MCI patients decreased gradually over time, while results of the normal group kept unchanged. There was no significant difference in LZC between two types of tasks. The two groups showed similar regularity in spatial distribution.
出处
《生物医学工程学杂志》
EI
CAS
CSCD
北大核心
2013年第5期972-975,共4页
Journal of Biomedical Engineering
基金
上海市教委自然科学创新重点项目资助(12ZZ099)
国家自然科学基金资助项目(61171032)
脑功能疾病调控治疗北京市重点实验室开放课题资助项目(2012NBTK02)
关键词
脑电
老年人
轻度认知障碍
Lempel—Ziv复杂度
Electroeneephalography（EEG）
The elderly
Mild cognitive impairment （MCI）
Lempel-Ziv complexity（I.ZC）
