摘要
目的 探讨CNTF基因多态性与运动员肌肉组织训练适应性的关系.方法 测定某院校体育专业215名无训练史学生CNTF基因型,并于训练过程中检测试验对象肱二头肌肌腹横截面积变化,检测其肌肉疲劳及肌肉损伤相关生化指标.分析基因多态性对检测结果的影响.结果 检测对象完成新训过程后,肱二头肌横截面积均有不同程度的增长,其中GG基因型增长幅度大于其他基因型（F=8.823,P＜0.05）.在新训结束时的体能考核后,各组检测对象相关指标仍高于对照组,但GG型检测对象血乳酸、血尿素氮、血清肌酸激酶值低于其他各组[（234.7 ±57.5）比（84.7±24.7）U,（5.8±0.8）比（4.3 ±0.6）mmol/L,（271.5 ±98.7）比（59.2±35.6）U]（P＜0.05）.结论 GG型检测肌肉横截面积增加较多,肌肉损伤相关血清指标增高较小;GG对象肌肉组织训练适应性优于GA、AA型.
Objective To explore the relationship between CNTF gene polymorphism and athletes training adaptation of muscle tissue.Methods A total of 215 new students without a training history CNTF genotype were recruited from a sports college.During training,the changes in test object biceps muscle belly cross-sectional area,muscle fatigue and muscle damage related biochemical indices were detected.And the impact of gene polymorphism was analyzed on the detection results.Results After training,biceps brachii muscle cross-sectional areas showed different degrees of growth and the GG gene type growth was greater than other genotypes（P 〈0.05）.At post-training physical examination,all subjects of muscle fatigue and muscle damage index were higher than those of the control group,but no obvious difference existed between examination groups.In basic training at the end of physical examination,the related indices of each group were higher than those of the control group,but the values of lactic acid,blood urea nitrogen and serum CK value were lower for object type GG than those for the other groups [（234.7 ± 57.5） vs （84.7 ± 24.7） U,（5.8±0.8） vs （4.3 ±0.6）mmol/L,（271.5 ±98.7） vs （59.2±35.6） U] （P 〈0.05）.Conclusion During training,muscle cross-sectional area of GG genotype grows more while the serum levels of muscle injury are significantly lower than those of other groups.In summary,GG genotype has better muscle training adaptation than GA and AA.
出处
《中华医学杂志》
CAS
CSCD
北大核心
2013年第37期2969-2971,共3页
National Medical Journal of China
关键词
肌疲劳
肌疾病
创伤和损伤
基因型
Muscle fatigue
Musclar diseases
Wounds and injuries
Genetype
