摘要
目的:研究天舒胶囊联合帕罗西汀治疗躯体形式障碍(SFDs)的疗效。方法:将76例SFDs的患者随机分为两组,观察组为:天舒胶囊联合帕罗西汀,对照组为:单用帕罗西汀,疗程为4周。两组在开始用药的2周均同时每晚服用氯硝西泮0.5-1mg。分别于治疗第2和第4周末观察比较两组躯体形式障碍临床症状改善情况及症状自评量表90项(SCL-90)躯体化因子分和汉密尔顿抑郁量表(HAMD)评分。结果:两组治疗后与治疗前相比,躯体形式障碍临床症状及SCL-90躯体化因子评分和HAMD评分均有明显改善(P<0.01);与对照组比较,观察组临床症状改善更好、更快(P<0.05)。结论:天舒胶囊联合帕罗西汀治疗躯体形式障碍,可促进其临床症状的缓解,提高治疗效果。
Objective: To investigate the clinical effects of Tianshu Capsule combined with paroxetine on the treatment of somatoform disorder. Methods: A total of 76 patients with somatoform disorder were randomly divided into 2 groups, the observed group and control group. Observed group was treated with Tianshu Capsule and paroxetine tablets. Control group was treated only with Paroxetine Tablets. The progress was 4 weeks. During the first two weeks, all the patients were treated with Clonazepam 0.5-1mg q.n. They were compared in the clinical symptoms, the factor score of SCL-90 and the score of HAMD at the last of 2nd and 4th week after the treatment in the two groups. Results: The clinical symptoms, the factor score of SCL-90 and the score of HAMD in two groups were significantly improved after treatment (P〈0.01), and the effect in observed group was faster and better than control group (P〈0.05). Conclusion: Tianshu Capsule combined with paroxetine improves clinical symptoms faster and has better efficacy in the treatment of somatoform disorder.
出处
《中华中医药杂志》
CAS
CSCD
北大核心
2013年第10期3099-3101,共3页
China Journal of Traditional Chinese Medicine and Pharmacy
基金
南通市课题资助项目(No.BK2012081)~~