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头孢唑林与中药熏洗治疗肛肠疾病术后切口感染疗效观察 被引量:18

Effect of cefazolin sodium combined with Chinese herbal fumigation on treatment of incision infections after anorectal disease surgery
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摘要 目的分析头孢唑林配合中药熏洗治疗肛肠疾病术后切口感染的临床疗效,探讨预防肛肠疾病术后切口感染的有效措施。方法对2007年1月-2011年1月外科治疗术后出现切口感染的肛肠疾病患者173例作为研究对象,根据治疗方法不同随机分为使用常规治疗的对照组患者86例及使用头孢唑林配合中药熏洗治疗的观察组患者87例,比较两组患者的治疗效果、疼痛评分、抑郁情绪评分等差异。结果治疗后观察组总有效率为97.70%、对照组为89.53%,组间比较差异有统计学意义(χ2=2.396,P<0.05);平均疼痛评分观察组为(3.84±0.72)分、对照组为(5.96±1.23)分,组间比较差异有统计学意义(t=2.843,P<0.05),且轻度、中度、重度疼痛观察组分别占79.31%、11.49%、9.20%,对照组分别占36.05%、44.19%、19.77%,两组比较,差异均有统计学意义(P<0.01);观察组平均抑郁情绪评分(4.53±0.91)分、对照组为(7.22±1.47)分,组间比较差异有统计学意义(t=2.742,P<0.05),各项指标观察组均显著优于对照组。结论对于肛肠疾病术后切口感染患者使用头孢唑林配合中药熏洗治疗,可以有效提高治疗效果,减轻患者疼痛,缓解其负面情绪。 OBJECTIVE To analyze the clinical efficacy of cefazolin sodium combined with Chinese herbal iumigation in the treatment of incision infections after anorectal disease surgery and explore effective measures for the prevention of postoperative infections. METHODS A total of 173 anorectal disease patients, who underwent the surgery from Jan 2007 to Jan 2011 and suffered from postoperative incision infections, were enrolled in the study and randomly divided into the control group with 86 cases and the observation group with 87 cases according to the treatment methods, then the control group was treated with the routine method, while the observation group was treated with cefazolin sodium combined with Chinese herbal fumigation, and the therapeutic effect, pain score, and depression score were compared between the two groups. RESULTS After the treatment, the total effective rate of the observation group was 97.70~//00, significantly higher than 89.53% of the control group, the difference was significant (Z2=2. 396,P〈0.05);. the average pain score was (3.84±0.72) points in the observation group, (5.96 ±1.23) points in the control group, the difference was significant (X2 =2. 843, P〈0.05) ; the patients with mild pain accounted for 79. 31% in the observation group , 36, 05% in the control group; the patients with moderate pain accounted {or 11.49% in the observation group, 44.19% in the control group the patients with severe pain accounted for 9.20% in the observation group, 19.77% in the control group, the difference between the two groups was significant. The average depression score of the observation group was(4.53±0.91) points, the control group (7. 22±1. 47) points, the difference between the two groups was significant (t= 2. 742, P〈0.05), all the indexes above of the observation group were significantly higher than those of the control group. CONCLUSION For the anorectal diseases patients with postoperative incision infections, the cefazolinsodium combined with Chinese herbal
出处 《中华医院感染学杂志》 CAS CSCD 北大核心 2013年第20期5042-5044,共3页 Chinese Journal of Nosocomiology
基金 临海市科技局科技计划项目(11M25)
关键词 头孢唑林 中药熏洗 肛肠疾病 切口感染 Cefazolin sodium Chinese herbal fumigation and washing Anorectal disease~ Incision infection
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