摘要
目的探讨同型半胱氨酸(Hcy)与原发性高血压不同危险分层的相关性。方法选择68例临床确诊的原发性高血压患者,按照《中国高血压防治指南》(2010修订版:第三版)规定的危险分层标准进行分组,分别为中危组41例和高危组27例,同时选择60例健康体检者设为健康对照组,试验过程中采用双盲法,分别测定Hcy浓度,进行组间对比,分析与原发性高血压的相关性。结果和对照组比较,随着危险程度增高,Hcy浓度也逐渐升高,差异有统计学意义(P<0.05)。结论 Hcy水平与原发性高血压患者的危险分层密切相关,是辅助诊断原发性高血压的良好指标,对疾病的预防具有积极作用。
Objective To explore the correlation between homocysteine （Hcy） and the different risk stratifica-tion of primary hypertension .Methods 68 patients with primary hypertension were divided into moderate-risk group （41 cases） and high-risk group （27 cases） according to Prevention and Control Guidelines of Hypertension in China （2010 revision ,the 3rd ed .） .60 healthy subjects were enrolled as control group .Concentration of Hcy was detected and compared between each group .Results Compared to control group ,concentration of Hcy increased with the in-creasing of risk stratification of primary hypertension （P〈0 .05） .Conclusion There could be close relationship be-tween Hcy level and the risk stratification of primary hypertension .Monitoring of Hcy level might be a fine indicator for the diagnosis and prevention of primary hypertension .
出处
《检验医学与临床》
CAS
2013年第17期2266-2267,共2页
Laboratory Medicine and Clinic
