期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

肺癌放化疗“实时”疗效评估方法的研究进展 被引量：6

Research progress of evaluating methods in real-time curative effect for radiochemotherapy in lung cancer
原文传递
导出
摘要 肺癌是世界范围内最常见的恶性肿瘤，保守估计，2012年美国的新发肿瘤中，肺癌位居第二，死亡率居首位¨引。目前肺癌总体生存率却仅有16％左右。随着“个体化”这一治疗理念的提出，根据每一个肺癌患者的肿瘤生物学特征及药物基因组学改变进行针对性治疗，是目前肺癌规范化治疗的准则。但由于肺癌的异质性，其耐药、复发和转移成为目前面临的难题。“生存期”是临床评价疗效好坏的金标准，而在处理个体患者时并不适用。对个体患者而言，只有当生存期的延长与“缓解率”和生活质量的提高相关联时才具有价值。而以CT、MRI等影像学技术为基础评估“缓解率”的方法，
作者 邹晶 徐兴祥 王大新 钱桂生
机构地区 江苏省扬州市苏北人民医院呼吸内科 江苏省扬州市苏北人民医院心内科 第三军医大学附属新桥医院呼吸病研究所
出处 《中华肺部疾病杂志（电子版）》 CAS 2013年第4期60-63,共4页 Chinese Journal of Lung Diseases(Electronic Edition)
关键词 肺癌 放化疗 疗效评估
分类号 R734.2 [医药卫生—肿瘤]
  • 相关文献

参考文献26

  • 1钱桂生.为提高我国呼吸系统疾病的诊治水平而努力[J].中华肺部疾病杂志（电子版）,2012,5(1):1-3. 被引量：54
  • 2Siegel R, Naishadham D, Jemal A. Cancer statistics, 2012[ J]. CA Cancer J Clin, 2012, 62(1) :10-29. 被引量：1
  • 3Hallqvist A, Bergman B, Nyman J. Health related quality of life in locally advanced NSCLC treated with high dose radiotherapy and concurrent chemotherapy or cetuximab-pooled results from two prospective clinical trials [ J ]. Radiother Oncol, 2012, 104 ( 1 ) :3944. 被引量：1
  • 4Ganguli A, Wiegand P, Gao X, et al. The impact of second-line agents on patients' health-related quality of life in the treatment for non-small cell lung cancer: a systematic review [ J]. Qual Life Res, 2013, 22(5) : 1015-1026. 被引量：1
  • 5石远凯,李峻岭,吴昌归,等.亚太地区含泰索帝方案一线治疗晚期非小细胞肺癌(NSCLC)患者生活质量(QOL)评估及与缓解率相关性的多中心Ⅲ期临床研究:中国患者亚组中期总结[C].第三届中国肿瘤内科大会教育集暨论文集.北京.中国协和医科大学出版社,2009.478-480. 被引量：1
  • 6Saad ED, Adamowicz K, Katz A, et al. Assessment of quality of life in advanced non-small-cell lung cancer: an overview of recent randomized trials [ J ]. Cancer Treat Rev, 2012, 38 (6) : 807-814. 被引量：1
  • 7Soussan M, Chouahnia K, Maisonobe JA, et al. Prognostic implications of volume-based measurements on FDG PET/CT in stage m non- small-cell lung cancer after induction chemotherapy [ J ]. Eur J Nucl Med Mol Imaging, 2013, 40(5) : 6684576. 被引量：1
  • 8Skoura E, Datseris IE, Platis I, et al. Role of positron emission tomography in the early prediction of response to chemotherapy in patients with non-small-cell lung cancer [ J]. Clin Lung Cancer, 2012, 13(3) :181-187. 被引量：1
  • 9Dahele M, Freeman M, Pearson S, et al. Early metabolic response evaluation after stereotactic radiotherapy for lung cancer: pilot experience with 18 F-fluorodeoxyglucose positron emission tomography-computed tomography [ J ]. Clin Oncol (R Coll Radiol), 2011, 23(5): 359-363. 被引量：1
  • 10Saga T, Koizumi M, Inubushi M, et al. PET/CT with 3'-deoxy- 3' -[ 18F] fluorothymidine for lung cancer patients receiving carbon- ion radiotherapy[ J ]. Nucl Med Commun, 2011, 32 (5) : 348-355. 被引量：1

二级参考文献34

  • 1Molina JR,Adjei AA,Jett JR.Advances in chemotherapy of non-small cell lung cancer[J].Chest,2006,130 (4):1211. 被引量：1
  • 2Fehm T,Sagalowsky A,Clifford E,et al.Cytogenetic evidence that circulating epithelial cells in patients with carcinoma are malignant[J].Clin Cancer Res,2002,8 (7):2073. 被引量：1
  • 3Pretlow TG,Schwartz S,Giaconia JM,et al.Prostate cancer and other xenografts from cells in peripheral blood of patients[J].Cancer Res,2000,60 (15):4033. 被引量：1
  • 4Muller P,Schlimok G.Bone marrow micrometastases of epithelial tumors:Detection and clinical relevance[J].J Cancer Res Clin Oncol,2000,126 (11):607. 被引量：1
  • 5Ge M J,Shi D,Wu QC,et al.Observation of circulating turnout cells in patients with non-small cell lung cancer by real-time fluorescent quantitative reverse transcriptase-polymerase chain reaction in peroperative period[J].J Cancer Res Clin Oncol,2006,(4):248. 被引量：1
  • 6Passlick B,Kubuschok B,Izbicki JR,et al.Isolated tumor cells in bone marrow predict reduced survival in node-negative non-small cell lung cancer[J].Ann Thorac Surg,1999,68 (6):2053. 被引量：1
  • 7Yasumoto K,Osaki T,Watanabe Y,et al.Prognostic value of cytokeratin-positive cells in the bone marrow and lymph nodes of patients with resected nonsmall cell lung cancer:A multicenter prospective study[J].Ann Thorac Surg,2003,76 (1):194. 被引量：1
  • 8Ring AE,Zabaglo L,Ormaerod MG,et al.Detection of circulating epitherlial cells in the blood of patients with breast cancer:Comparison of three techniques[J].Br J Cancer,2005,92 (5):906. 被引量：1
  • 9Brandt B,Junker R,Griwatz C,et al.Isolation of prostatederived single cells and cell clusters from human peripheral blood[J].Cance Res,1996,56 (20):4556. 被引量：1
  • 10Benez A,Geiselhart A,Handqretinqer R,et al.Detection of circulating melanoma cells by immunomagnetic cell sorting[J].J Clin Lab Anal,1999,13 (5):229. 被引量：1

共引文献65

同被引文献42

  • 1Jemal A, Bray F, Center MM, et al. Global cancer statistics [ J ]. CA Cancer J Clin, 2011, 61(2) : 69-90. 被引量：1
  • 2Tyldesley S, Boyd C, Schulze K, et al. Estimating the need for radiotherapy for lung cancer: an evidence-based, epidemiologic approach [J]. Int J Radiat Oncol Biol Phys, 2001, 49(4) : 973- 985. 被引量：1
  • 3Socha J, Kolodziejczyk M, Kpka L. Outcome after PET-CT based radiotherapy for non-small cell lung cancer [ J]. Pneumonol Alergol Pol, 2013, 81(1): 30-39. 被引量：1
  • 4Osti MF, Agolli L, Valeriani M, et al. Image guided hypofractionated 3-dimensianal radiation therapy in patients with inoperable advanced stage non-small cell lung cancer [ J]. Int J Radiat Oncol Biol Phys, 2013, 85(3) : e157-163. 被引量：1
  • 5Kioi M, Vogel H, Schultz G, et al. Inhibition of vasculogenesis, but not angiogenesis, prevents the recurrence of glioblastoma after irradiation in mice [J]. J CIin Invest, 2010, 120(3) : 694-705. 被引量：1
  • 6Ahn GO, Brown JM. Matrix metalloproteinase-9 is required for tumor vasculogenesis but not for angiogenesis : role of bone marrow-derived myelomonocytic ceils [J]. Cancer Cell, 2008, 13(3) : 193-205. 被引量：1
  • 7Chen FI-I, Chiang C,S, Wang CC, et al. Radiotherapy decreases vascular density and causes hypoxia with maerophage aggregation in TRAMP- C1 prostate tumors [ J]. Clin Cancer Res, 2009, 15 (5) : 1721- 1729. 被引量：1
  • 8Priceman SJ, Sung JL, Shaposhnik Z, et al. Targeting distinct tumor- infiltrating myeloid cells by inhibiting CSF-1 receptor: combatingtumor evasion of antiangiogenic therapy [J]. Blood, 2010, 115 (7) : 1461-1471. 被引量：1
  • 9Tang DG, Conti CJ. Endothelial cell development, vasculogenesis, angiogenesis, and tumor neovascularization : an update [ J ]. Semin Thromb Hemost, 2004, 30( 1 ) : 109-117. 被引量：1
  • 10Stephens TC, Currie GA, Peacock JH. Repopulation of gamma- irradiated Lewis lung carcinoma by malignant ceils and host macrophage progenitors [ J ]. Br J Cancer, 1978, 38 (5) : 573- 582. 被引量：1

引证文献6

二级引证文献24

中华肺部疾病杂志（电子版）
2013年 第4期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部