摘要
目的:通过对梅毒患者的流行病学分析,为梅毒的预防、早发现及治疗提供理论依据。方法:对2006-2010年1 219例梅毒患者各年人数、性别比例、年龄分布、职业、文化程度、传染来源、病期、同时感染其他性传播疾病情况及治疗情况进行回顾性分析。结果:梅毒年均增长率为28.46%,男性患者共计748例,女性471例,男女比例为1.59:1,非婚性接触者863例占所有患者的70.80%,378例患者同时并发其他性传播疾病,占全部患者的31.01%,普鲁卡因青霉素G与米诺环素治疗梅毒,快速血浆反应素试验(RPR)转阴情况无统计学差异(P>0.05)。结论:梅毒患者人数呈逐年上升趋势,男性患者多于女性,患者中以早期患者为主,潜伏梅毒比例逐年增加,且梅毒往往同时感染其他性传播疾病,口服米诺环素可作为替代治疗方案。
Objective： Clinical data of syphilitic patients from our department were analyzed in order to provide detailed clinical information for the prevention, early detection and treatment of syphilis. Methods： Parameters such as the number of patients per year, gender, age, occupation, education, source of infection, stage of syphilis, other sexually transmitted diseases （STDs） and treatment were retrospectively analyzed from 1 219 syphilitic patients from 2006 to 2010. Results： The average annual increase rate of syphilis was 28.46%, 748 patients were males and 471 patients were females. The male-to-female ra- tio was 1.59：1. Eight hundred and sixty-three patients （70.80%） had a history of extra-marital sex; 378 patients （31.01%） co- infected with other sexually transmitted diseases. The rates of RPR tests reverting to non-reactive were not significantly differ- ent between the patients treated with procaine penicillin and minocycline （P 〉 0.05）. Conclusions： The number of syphilitic patients has been increasing year by year. There are more male patients than female patients. A large portion of patients are early stage of syphilis. The number of latent syphilitic patients is increasing yearly. Syphilis is often co-infected with other sexually transmitted diseases. Minocycline could be an alternative for treating syphilis.
出处
《临床皮肤科杂志》
CAS
CSCD
北大核心
2013年第10期587-589,共3页
Journal of Clinical Dermatology
关键词
梅毒
流行病学
syphilis
epidemiology
