摘要
目的探索鼻咽癌诱导化疗后放射治疗靶区勾画的有效影像学检查方法。材料与方法选择21例鼻咽癌诱导化疗后的增强CT与MR图像,由2名医师观察MRI增强T1WI横断面、T2WI压脂横断面及CT增强横断面图像(三种图像)上病灶显示情况及对周围结构的侵犯,并进行对比分析。结果 21例中,2例诱导化疗后原发病变消失。19例显示原发肿瘤,共131个层面显示病灶,在三种图像上显示病变边缘清楚的分别为117层(89.3%)、103层(78.6%)和52层(39.7%),三种图像均显示病变边缘清楚的有5例,这5例在CT图像上病变明显强化。10例头长肌受侵在MR图像上均显示清楚,在CT图像上仅4例强化明显者可确定。颅底骨结构受侵在CT和MR图像上显示无明显差异。结论 MRI显示鼻咽癌的边界及对头长肌的侵犯优于CT;在增强CT图像上,如病变强化明显,边界显示清楚或诱导化疗后,原发病灶消失或颅底广泛受侵者可直接在CT图像上勾画靶区。
Objective： To study the medical imaging examination method for drawing the outline of the target areas after induction chemotherapy of nasopharyngeal carcinoma.Materials and Methods： CT and MR enhancement images of 21 patients with nasopharyngeal carcinoma after induction chemotherapy were collected.The transverse images of MR T1WI enhancement,T2WI fat-suppression and CT enhancement（three kinds of images） were observed and analyzed by two experienced doctors.Result： The primary lesion is disappeared after induction chemotherapy in 2 cases.Primary tumor lesions were showed in 19 cases and a total of 131 sections.On the three kinds of images,the lesion showed clearly boundary in 117 sections（89.3%）,103 sections（78.6%） and 52 sections（39.7%） respectively.The lesion simultaneously displayed well-defined boundary on three kinds of images in 5 cases,These lesions of 5 cases showed obvious reinforcement on the contrast-enhanced CT images.The longus capitis was invaded in 10 cases on MR images,only 4 obviously enhancement cases on enhanced CT images.It is not significant differences between CT images and MR images in displaying the invasion of basis cranii.Conclusions： MRI is superior to CT in showing the boundary of nasopharyngeal carcinoma and judging the invasion of longus capitis.We can directly draw the outline of the target areas on the CT images,when the enhancement of the lesion is obvious and the fringe is clear on enhanced-CT images,or the primary lesion is disappeared after induction chemotherapy,or the basis cranii is widely invaded.
出处
《磁共振成像》
CAS
CSCD
2013年第5期330-334,共5页
Chinese Journal of Magnetic Resonance Imaging
关键词
鼻咽肿瘤
磁共振成像
体层摄影术
X线计算机
病例对照研究
Nasopharyngeal neoplasms
Magnetic resonance imaging
Tomography
X-ray computed
Case-control studies
