摘要
目的:对马莲鞍根75%乙醇提取物的大孔树脂柱60%乙醇洗脱物进行化学成分研究。方法:利用硅胶柱色谱、ODS柱色谱、制备液相等分离手段进行化学成分的分离,再通过核磁共振波谱法确定其化学结构。结果:经分离得到3个化合物均为白色粉末;核磁共振波谱图,确定其为强心苷类化合物,分别为16-O-acetylperiplogenin(1),periplogenin 3-O-β-D-digitoxoside(2),digitoxigenin gentiobioside(3),其中,化合物1为种内首分。结论:本方法对马莲鞍的化学成分研究具有较好的应用价值。能应用于马莲鞍的进一步开发。
Objective：To study Malian saddle 75% ethanol extract of the root macroporous resin column 60% ethanol elution the chemical constituents.Method：Used such as silica gel Column chromatography,ODS column chromatography and preparative high performance liquid separated means to separate the chemical components,and then by NMR determined its chemical structure.Result：The isolated three white powder compounds;NMR chart determine if it was a cardiac glycosides.The three compounds were 6-O-acetylperiplogenin（1）,periplogenin 3-O-β-D-digitoxoside（2）,digitoxigenin gentiobioside（3）,where in the compound 1 was a species within the first minute.Conclusion：The method Malian chemical constituents of the saddle has a good application value.Can be applied to the further development of Malian saddle
出处
《中国医学创新》
CAS
2013年第26期142-144,共3页
Medical Innovation of China
关键词
马莲鞍
化学成分
提取分离
结构鉴定
Malian saddle
Chemical composition
Extraction
Structure identification
