摘要
目的：观察地佐辛联合舒芬太尼用于术后静脉自控镇痛（PCIA）的临床效果。方法：选择ASAⅠ~Ⅱ级择期行全麻手术的患者60例,全部采用气管插管全凭静脉麻醉,术后行PCIA。将患者随机分为舒芬太尼组（S组）和地佐辛联合舒芬太尼组（DS组）,每组30例。S组配方：舒芬太尼2.5μg/kg＋格拉司琼3 mg加0.9%氯化钠注射液稀释至100 ml;DS组配方：地佐辛0.2 mg/kg＋舒芬太尼1.5μg/kg＋格拉司琼3 mg加0.9%氯化钠注射液稀释至100 ml。观察两组患者术后2、6、12、24、48 h视觉模拟评分（VAS）、镇静程度评分（Ramesy）、不良反应的情况。结果：两组配方均能为患者提供良好的术后镇痛,DS组患者的VAS评分、Ramesy镇静评分低于S组,且不良反应更少。结论：地佐辛联合舒芬太尼用于术后静脉自控镇痛,镇痛效果确切且不良反应少,可安全有效地用于临床患者术后自控静脉镇痛。
Objective：To evaluate the anagesia effects of PCIA with docozine and sufentanil.Method：Sixty patients with ASA Ⅰ-Ⅱ that were scheduled for operation under intravenous analgesia with tube insertion and treated with PCIA after the operation were selected and divided into decozine group（Group D,n=30）,and decozine combining sufentanil group（Group DS,n=30）.PCIA gradients used for Group S and group DS was sufentanil 2.5 μg/kg＋Granisetron Hydrochloride 3 mg;and decozine 0.2 mg/kg＋sufentanil 1.5 μg/kg＋ Granisetron Hydrochloride 3 mg,seperately;which were diluted to be 100 ml by adding saline.VAS,Ramesy scores and side effects were recorded and compared.Result：DS group showed better outcomes regarding to the VAS score,Ramesy score comparing with group S（P〈0.05）.Group DS also showed less side effects.Conclusion：Decozine combining with sufentanyl in PCIA exhibits better anaglgesia effect with less side effects,and it＇s worth for clinical application.
出处
《中国医学创新》
CAS
2013年第26期32-33,共2页
Medical Innovation of China
关键词
地佐辛
舒芬太尼
术后镇痛
Decozine
Sufentanil
Postoperative analgesia
