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抗流感中药冰香散提取工艺的正交实验研究 被引量:1

Optimization of extraction technology of Bing-xiang Powder volatile oil by othogonal experiment
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摘要 目的优选冰香散的最佳提取工艺。方法以得油率为评价指标,采用正交试验设计法考察颗粒粒度、加水量、浸泡时间、蒸馏时间4个因素对提取效果的影响,通过综合评分筛选出冰香散的最佳提取工艺。结果综合考虑各因素的影响及生产实际需要,确定的最佳提取工艺为:冰香散药材打成中粉,加入10倍量水,浸泡1.5小时,共水蒸馏提取6小时。结论该工艺条件对冰香散挥发油的生产具有一定的指导和参考意义。 Objective To optimize the extraction process of Bing-xiang Powder volatile oil. Methods Extraction yields of Bing - xiang Powder volatile oil was regarded as investigation index, and particle size, the amount of water,soaking time and duration on extraction were evaluated by orthogonal experimental design, and the best extraction process was statistically analyzed and screened by index comprehensive evaluation method. Results Considering the effects of three factors and actual production process synthetically, the optimum condition of extraction process was that the medium powder, in 10 folds water, soaked 1.5 hours, extracted 6 hours. Conclusion The optimum extraction process will have some instruction meaning and reference value to the production of Bing - xiang Powder volatile oil.
出处 《环球中医药》 CAS 2013年第7期518-520,共3页 Global Traditional Chinese Medicine
基金 国家自然科学基金(81072948) 广东省建设中医药强省立项资助科研课题(2010397)
关键词 冰香散 挥发油 正交设计 提取工艺 Bing-xiang Powder Volatile oil Extraction process Orthogonal design
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  • 1李春生.对人高致病性禽流感发病规律和中医药治疗方案的初步探讨[J].中华中医药杂志,2006,21(3):134-139. 被引量:14
  • 2Barroso S P, Nico D, Nascimento D, et al. Intranasalimmunization with pressure inactivated avian influenza elicits cellular and humoral responses in mice[J]. PLoS One, 2015, 10 (6) : e0128785. 被引量:1
  • 3Park K S, Lee J, Ahn S S, et al. Mucosal immunity induced by adenovirus-based HSN1 HPAI vaccine confers protection against a lethal H5N2 avian influenza virus challenge[J]. Virology, 2009, 395 (2): 182. 被引量:1
  • 4Srivastava A, Gowda D V, Madhunapantula S V, et al. Mucosal vaccines: a paradigm shift in the development of mueosal adjuvants and delivery vehicles[J]. APMIS, 2015, 123(4) : 275. 被引量:1
  • 5Ansaldi F, Canepa P, Parodi V, et al. Adjuvanted seasonal influenza vaccines and perpetual viral metamorphosis: the importance of cross-protection[J]. Vaccine, 2009, 27(25-26) : 3345. 被引量:1
  • 6Joseph A, Itskovitz-Cooper N, Samira S, et al. A new intranasal influenza vaccine based on a novel polycationic lipid-ceramide carbamoyl-spermine(CCS)I. Immunogenicity and efficacy studies in mice[J]. Vaccine, 2006, 24(18) : 3990. 被引量:1
  • 7Mazur I, Wurzer W J, Ehrhardt C, et al. Acetylsalicylic acid (ASA) blocks influenza virus propagation via its NF-kappaB- inhibiting activity[J]. Cell Microbiol, 2007, 9(7): 1683. 被引量:1
  • 8Takahashi E, Kataoka K, Fujii K, et al. Attenuation of inducible respiratory immune responses by osehamivir treatment in mice infected with influenza A virus[J]. Microbes Infect, 2010, 12(10) : 778. 被引量:1
  • 9Whitsett J A, Alenghat T. Respiratory epithelial cells orchestrate pulmonary innate immunity[Jl. Nat Immunol, 2015, 16(1) : 27. 被引量:1
  • 10Jones T, Cyr S L, Allard F, et al. A nasal proteosome influenza vaccine containing baculovirus-derived hemagglutinin induces protective mucosal and systemic immunity I Jl. Vaccine, 2003, 21(25-26): 3706. 被引量:1

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