摘要
氧化型低密度脂蛋白在动脉粥样硬化的发生发展过程中具有重要的作用,是导致此病发生的独立致病因素.其主要是通过细胞毒性、化学趋化性以及免疫原性等诱导血管内皮细胞损伤,趋化单核细胞与内皮细胞的黏附,巨噬细胞泡沫化,诱发炎症反应,加重动脉粥样硬化.就近年来氧化型低密度脂蛋白与动脉粥样硬化关系的研究以及中药对其进行的干预作用予以综述,以期为寻找有效的防治动脉粥样硬化的中药提供一定的帮助.
Ox- LDL is an independent disease-causing factor. It can lead to atherosclerosis. It mainly produces cell toxicity, chemical chemotaxis and immunogenicity though inducing endothelial cell damages, chemokines mono- cyte and endothelial cell adhesion, or foamy macrophages. At last it also induces inflammation and worsens athero- sclerosis. This paper gives a summary review of the researches on the relationship between Ox - LDL and athero- sclerosis and the antioxidant effect of traditional Chinese medicine in hope of finding the effective traditional Chinese medicine for the treatment in this asr）ect.
出处
《云南民族大学学报（自然科学版）》
CAS
2013年第5期313-316,共4页
Journal of Yunnan Minzu University:Natural Sciences Edition
