摘要
目的：对比分析早期先兆流产与稽留流产患者血清中瘦素的差异,以帮助临床判断患者病情及预后。方法：回顾性收集我计生中心及龙岗区第二人民医院收治,经临床证实的早期先兆流产、稽留流产患者及正常妊娠健康孕妇各40例,分别于孕5、6、7周测量3组孕妇血清瘦素水平,对比分析3组孕妇血清瘦素水平的差异及变化趋势。结果：孕5~7周,正常妊娠组及早期先兆流产组孕妇随孕周的增加,血清瘦素浓度随之增加;稽留流产组孕妇血清瘦素浓度,随孕周增加而下降。稽留流产组孕妇血清瘦素水平明显均低于正常妊娠组及早期先兆流产组（P〈0.05）;正常妊娠组及早期先兆流产组血清瘦素水平差异无显著性（P〉0.05）。结论：稽留流产者血清瘦素浓度明显降低,并且随孕周增加而进一步降低,早期先兆流产血清瘦素浓度随孕周增加而逐渐增加,检测其变化对早期判断患者病情及预后有一定价值。
Objective： To discuss the difference of serum leptin level in early threatened abortion and missed abortion to aid in diagnosis.Method：Each 40 reported cases of early threatened abortion,normal pregnancy and missed abortion were collected and analyzed.The level of serum leptin was determined during 5~7 gestational weeks.The difference of serum leptin level and trends were comparative analysesed.Result：In 5~7 gestational weeks,the serum leptin level increased with the progress of pregnancy in early threatened abortion and normal pregnancy team;the serum leptin level decreased with the progress of pregnancy in missed abortion team.The serum leptin level in missed abortion team was significantly less than that in the others（P＆lt;0.05）.There was no statistical difference between early threatened abortion and normal pregnancy team（P＆gt;0.05）.Conclusion： The level of serum leptin in missed abortion significantly will decrease,further reducing with the increase of the gestational weeks;the level of serum leptin in early threatened abortion will increase with the increase of the gestational weeks.The determination of serum leptin could be useful to establishing the severity and prognosis of clinic.
出处
《中国医药导刊》
2013年第7期1113-1114,共2页
Chinese Journal of Medicinal Guide
基金
深圳市龙岗区2012年度科技计划医疗项目:YS2012004
关键词
先兆流产
稽留流产
血清瘦素
Early threatened abortion
Missed abortion
Serum leptin
