摘要
炎症性肠病(IBD)包括克罗恩病(CD)和溃疡性结肠炎(UC),是一类病因和发病机制尚不十分明确的肠道慢性非特异性疾病。近年来其发病率呈上升趋势,但到目前为止还没有找到彻底治愈的方法。肠道干细胞是成体干细胞的一种,主要分布在肠道的隐窝,其在修复损伤的黏膜中发挥重要作用。本文就肠道干细胞与IBD的关系作一概述。
Inflammatory bowel disease （IBD） including Crohn＇ s disease （CD） and ulcerative colitis （UC）, is a kind of chronic diseases of which the etiology and pathogenesis are still not very clear. Its incidence is rising in recent years, but so far the complete cure has not been found. Intestinal stem cell is a kind of adult stem cell and it mainly dis- tributed in the intestinal crypts. It plays an improtant role in repairing the injured mucosa. In this paper, a comprehen- sive overview is made about the relationship between intestinal stem cells and IBD.
出处
《胃肠病学和肝病学杂志》
CAS
2013年第8期717-719,共3页
Chinese Journal of Gastroenterology and Hepatology
基金
哈尔滨市科委青年科技创新人才基金(2018rfqys103)
关键词
炎症性肠病
临床特点
肠道干细胞
修复机制
分子调控
Inflammatory bowel disease
Clinical charecteristics
Intestinal stem cells
Repair mechanism
Molecu-lar regulation
