摘要
目的:探讨胚胎性横纹肌肉瘤(embryonal rhabdosarcoma,ERMS)的临床病理学特征。方法:对1例ERMS进行大体、组织病理学和免疫组化染色观察。结果:镜下肿瘤细胞弥漫分布,排列呈片状,巢状,瘤细胞较小,呈圆形,核深染,居中或偏位,胞浆少,核分裂易见。免疫组化Vimentin++,Desmin+。结论:胚胎性横纹肌肉瘤是一罕见的高度恶性软组织肿瘤,结合临床病理学特征及免疫组化,可作出正确诊断。
Objective：To investigate the clinical and pathological features of embryonal rhabdosarcoma（ERMS）.Methods：The clinical data were retrospectively analyzed of one case of ERMS.Histopathological and immunohistochemical changes of the tumor were also observed in the paraffin-embedded tissue samples.Results：Microscopically,tumor cells shaped aerie and sheet.The tumor cells with abundant and eosinophilic cytoplasm were diffusely distributed.Immunohistochemically,It was positive for Vimentin and Desmin.Conclusion：ERMS in nasal cavity of adult is a high grade malignant soft tissue neoplasm.And it is rarely to be found.Careful analysis of the clinicopathological features and immunohistochemisitry will be helpful to make accurate diagnosis.
出处
《现代肿瘤医学》
CAS
2013年第9期2119-2120,共2页
Journal of Modern Oncology
关键词
胚胎性横纹肌肉瘤
病理诊断
免疫组化
鉴别诊断
预后
embryonal rhabdosarcoma
pathological diagnosis
immunohistochemical
differential diagnosis
prognosis
