摘要
目的探讨高尿酸血症(HUA)患者尿微量清蛋白与肌酐比值(ACR)的临床价值。方法随机选取符合原发性HUA诊断标准的90例患者作为患者组,90例性别、年龄相当的健康体检者作为对照组,两组人群分别进行ACR、血清肌酐(Scr)、血尿素氮(BUN)、血尿酸(UA)检测,然后对各项检测数据进行统计分析。结果患者组和对照组比较,ACR的差异有统计学意义(P<0.05),Scr差异无统计学意义(P>0.05)。患者组ACR与Scr呈明显正相关(r=0.475,P<0.05);对照组ACR与Scr无明显相关性(r=-0.346,P=0.135)。结论 ACR是诊断HUA患者早期肾损伤良好的实验室检查指标,HUA患者应定期检查ACR,及早预防肾损伤的发生发展。
Objective To study the clinical value of urinary microalbumin to creatinine ratio（ACR） in patients with hyperurice- mia（HUA）. Methods 90 patients with primary HUA were enrolled in this study as patients group,90 healthy people were enrolled as control group,The two groups were similar in age and sex ratio. ACR, serum creatinine（Scr）, blood urea nitrogen（BUN）, serum uric acid（UA） were detected in each group respectively. After that correlation and statistic analysis were did. Results Between patients group and control group, there was significant difference in ACR（P〈0.05）, Scr showed no significant difference（P〉0.05）. In patients group ACR showed a positive correlation with Scr（r= 0. 475, P〈0.05）, while ACR and Scr showed no significant corre- lation in control group（r=-0. 346,P=0. 135）. Conclusion ACR is a good laboratory indicator for early diagnosis of renal injury in patients with HUA. Patients with HUA should periodically do ACR check to prevent the occurrence and development of renal injury.
出处
《国际检验医学杂志》
CAS
2013年第15期1963-1964,共2页
International Journal of Laboratory Medicine
