摘要
目的探讨紫杉醇+顺铂方案联合同步放疗治疗中晚期食管癌的临床疗效。方法 2011年3月至2012年3月期间,本院诊治的60例中晚期食管癌患者,根据随机数字法,将其分为对照组(单纯放疗)和观察组(紫杉醇+顺铂方案联合同步放疗),每组各30例,对两组近期疗效、不良反应,以及1年生存率,进行观察和比较。结果与对照组相比,观察组的总有效率、1年生存率均明显升高,P<0.05,差异有统计学意义,而两组不良反应发生率比较,差异没有统计学意义,P>0.05。结论对于中晚期食管癌患者,同步放疗联合紫杉醇+顺铂(TP)方案治疗疗效显著,显著改善患者的预后质量。
Objective To investigate the clinical efficacy of paclitaxel + cisplatin regimen combined with radiotherapy in treatment of advanced esophageal cancer. Methods From March 2011 to March 2012,60 cases of advanced esophageal cancer patients in our hospital,according to the method of random number,which was divided into control group ( radiotherapy) and observation group ( paclitaxel + cisplatin combined with concurrent radiotherapy) ,30 cases in each group,two groups of curative effect,adverse reaction,and the 1 year survival rates,were observed and compared. Results Compared with control group,the total effective rate of observation group,1 year survival rates were significantly increased,P 0. 05,the difference was statistically significant,and the adverse reactions of the two groups were compared,the difference was not statistically significant,P 0. 05. Conclusion For the patients with advanced esophageal cancer,radiotherapy combined with paclitaxel + cisplatin ( TP) regimen in the treatment of a significant effect,significantly improve the prognosis of the patients’quality of.
出处
《中国实用医药》
2013年第24期40-41,共2页
China Practical Medicine
关键词
同步放疗
紫杉醇
顺铂
中晚期食管癌
Radiotherapy
Paclitaxel
Cisplatin
Advanced esophageal cancer