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不同类型冠心病心绞痛患者同型半胱氨酸及脑利钠肽水平的变化及其临床意义 被引量:5

Changes and Clinical Significance of Homocysteine and Brain Natriuretic Peptide Level in Patients with Different Types of Coronary Heart Disease and Angina Pectoris
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摘要 目的探讨脑利钠肽(BNP)和同型半胱氨酸(Hcy)在不同类型冠心病心绞痛患者中的变化及其临床意义。方法选择我院行冠状动脉造影检查确诊为冠心病的患者160例,将其按照心绞痛类型分为稳定型心绞痛组(SAP组)60例和不稳定型心绞痛组(UAP组)100例,测定两组患者的血清BNP、Hcy水平。结果 UAP组患者血清BNP和Hcy水平均高于SAP组,差异有统计学意义(P<0.05)。结论 BNP和Hcy参与冠心病的发展过程,监测这些炎性指标水平可为临床病情分级和预后判断提供参考价值。 Objective To discuss the change and clinical significance of brain natriuretie peptide (BNP) and homo- cysteine (Hey) in patients with different types of coronary heart disease and angina peetoris. Methods 160 eases with coronary heart disease was chosen in our hospital, who were examined by CAG. According to the type of angina peetoris, they were divid- ed into stable angina group ( SAP group) 60 cases and unstable angina pectoris group ( UAP group) I00 eases, the level of serum BNP, Hey in two groups were determined. Results The level of serum BNP and Hey in in UAP group were higher than those of SAP group, the difference were statistically significant ( P 〈 0. 05 ). Conclusion BNP and Hey play an important part in the progress of coronary heart disease, and monitoring these levels can provide a reference value for the clinical classification and prognosis of illness.
出处 《实用心脑肺血管病杂志》 2013年第9期14-15,共2页 Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
关键词 冠心病 心绞痛 利钠肽 同型半胱氨酸 Coronary heart disease Angina peetoris Natriuretie peptide, brain Homoeysteine
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