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注意力缺陷多动障碍与多巴胺、去甲肾上腺素关系的研究进展 被引量：12

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摘要 注意力缺陷多动障碍(attention deficit hyperactivity disorder,ADHD)发病机制至今不明,其中讨论最热门的是多巴胺系统,其次是去甲肾上腺素系统。两者同属于单胺类神经递质,在生物合成、消除、酶降解及受体等方面有一定的相通性和特异性。本文综述了以上各个因素与ADHD发病及治疗的关系,多巴胺和去甲肾上腺素在ADHD发病及治疗方面具有双重作用,单独研究某个因素或某个系统具有一定的局限性。药物治疗研究过多侧重于单纯神经递质水平的变化,虽可以短期内明显改善ADHD核心症状,却忽视了对长期治疗效果的研究,尤其是ADHD共患病,从而也局限了ADHD的治疗。
作者 雷爽 韩新民
机构地区 南京中医药大学
出处 《中国儿童保健杂志》 CAS 北大核心 2013年第9期953-955,共3页 Chinese Journal of Child Health Care
基金 国家自然科学基金(81273801) 国家级重点学科南京中医药大学中医儿科学科第二期开放研究课题(EZK2012009) 江苏省2012年度普通高校研究生科研创新计划项目(CXZZ12_0613)
关键词 ADHD 多巴胺 去甲肾上腺素
分类号 R749.94 [医药卫生—神经病学与精神病学]
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参考文献28

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二级参考文献10

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中国儿童保健杂志
2013年 第9期

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