摘要
目的观察左西孟坦治疗老年重度心力衰竭的疗效及临床应用价值。方法将老年重度心力衰竭患者80例随机均分为观察组与对照组。两组均予以常规治疗,对照组予以静脉维持泵注5ug/(kg.min)的多巴酚丁胺,持续24h;观察组予以静注左西孟坦,初始负荷量为12ug/kg,10min后静注0.1ug/(kg.min),然后静脉滴注0.25～1.0ug/(kg.min)。结果观察组的治疗总有效率明显较对照组更高(P<0.05),治疗2w以后,观察组各项指标较对照组改善更为明显(P<0.05)。结论左西孟坦治疗老年重度心力衰竭具有较好的临床疗效,安全可靠,患者的耐受性较好,值得临床推广应用。
Objective To analysis efficacy and clinical application value of levosimendan in the treatment of elderly patients with severe heart failure. Methods A total of 80 elderly patients with severe heart fail-ure, randomly divided into observation group and control group. The two groups are to be the conventional treatment, the control group, to be intravenous maintain infusion 5ug/（ kg ~ min） of dobutamine, continu- ous 24h; observation group was treated with intravenous levosimendan initial load 12ug/kg, 10min after intravenous 0.1 ug/（ kg. min）, then intravenous infusion of 0.25 - 1.0 ug/（ kg .rain）. Results The total effective rate of the observation group was significantly higher than the control group （ P 〈 0.05 ）, af- ter two weeks of treatment, the indicators of the observation group than in the control group improved more significantly （P 〈 0.05 ）. Conclusion Levosimendan better clinical efficacy for the treatment of elderly patients with severe heart failure, safe, reliable, and better tolerated by patients, worthy of promotion in clinical application.
出处
《现代诊断与治疗》
CAS
2013年第8期1695-1697,共3页
Modern Diagnosis and Treatment
关键词
心力衰竭
老年患者
左西孟坦
临床疗效
价值
Heart failure
Elderly patients
Levosimendan
Clinical efficacy
Value
