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左西孟旦对慢性收缩性心力衰竭患者左心室功能及最大摄氧量的影响 被引量:9

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摘要 目的观察左西孟旦对慢性收缩性心力衰竭(CHF)患者左室功能及心肺运动功能的影响。方法将69例CHF患者随机分为对照组32例及左西孟旦组37例,两组均予抗CHF的常规治疗,左西孟旦组在此基础上加服左西孟旦,0.05~0.1μg/(kg·min)连续静滴24h。1周后复查,观察两组治疗前后临床疗效、心脏射血分数、心肺运动试验参数最大摄氧量。结果治疗1周后左西孟旦组与对照组治疗有效率分别为59.45%、34.38%,两组比较,P〈0.01。左西孟旦组与对照组心脏射血分数分别为0.49%±0.12%、0.44%±0.09%,最大摄氧量分别为(24.3±5.5)、(20.3±7.0)mL/(kg·min),两组比较,P均〈0.05。左西孟旦组观察期间3例出现室性早搏,调整剂量后好转,无因不能耐受停药者。结论左西孟旦可改善CHF患者左室功能,提高运动耐量,且较为安全。
机构地区 威海市立医院
出处 《山东医药》 CAS 2013年第31期74-75,共2页 Shandong Medical Journal
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