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瓜蒌皮在痰浊内阻证冠心病治疗中的应用 被引量:16

Application of pericarpium trichosanthis injection in the treatment of phlegm stasis syndrome of coronary heart disease
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摘要 痰浊内阻证冠心病的发病率逐年升高,在冠心病中医证侯类型分布中已居首位。对于痰浊内阻证冠心病的治疗应强调痰瘀同治,配伍化痰药物。瓜蒌薤白汤是治疗痰浊内阻证冠心病的经典方剂,基础药理学研究也发现瓜蒌皮提取物具有扩张冠状动脉、增加冠脉血流量,改善心肌供血、减低心肌耗氧、降低血清胆固醇、甘油三酯和低密度脂蛋白等作用。以痰瘀同治为理论基础研制的瓜蒌皮注射液对于痰浊内阻证冠心病有较好的疗效。 The morbidity of phlegm stasis syndrome of coronary heart disease has been increased year by year and ranked the lead in the TCM syndrome type distribution of coronary heart disease. For the treatment of phlegm stasis syndrome of coronary heart disease, the synchronic treatment of phlegm and blood stasis and the compatibility of phlegm drugs should be emphasized. Gualou Xiebai decoction is a classic prescription for the treatment of this disease. Basis pharmacology research also revealed that The extract of Trichosanthes kirilowii pericarp could dilate coronary artery and increase coronary blood flow, improve myocardial ischemia, reduce the consumption of myocardial oxygen, serum cholesterol and triglyceride and low-density lipoprotein and so on. Pericarpium trichosanthis injection manufactured based on the theory of the synchronic treatment of phlegm and blood stasis has better curative effect on phlegm stasis syndrome of coronary heart disease.
出处 《上海医药》 CAS 2013年第17期25-28,共4页 Shanghai Medical & Pharmaceutical Journal
关键词 痰浊内阻 冠心病 瓜蒌皮 瓜蒌皮注射液 phlegm stasis syndrome coronary heart disease pericarpium trichosanthis pericarpium trichosanthis injection
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