摘要
目的通过对慢性心力衰竭(chronic heart failure,CHF)患者血清中同型半胱氨酸(Homocysteine HCY)和高敏C反应蛋白(HS-CRP)的检测,探讨HCY和HS-CRP作为CHF危险因子在CHF临床应用的价值。方法在奥林巴斯AU640全自动生化分析仪上检测实验组和对照组的血清样本中HCY和HS-CRP含量,并对其检测结果进行分析。结果实验组血清Hcy和HS-CRP含量明显高于对照组,两组比较,差异有统计学意义或高度统计学意义(P<0.05或P<0.01);CHF各级患者单项检测与联合检测的阳性检出率结果比较,差异有统计学意义(P<0.05)。结论血清HCY和HS-CRP浓度检测可作为CHF危险因子的常规检测指标,有助于提高CHF的阳性检出率,其浓度水平变化对CHF的临床诊断、治疗和预后具有一定参考价值。
Objective Based on chronic heart failure（chronic heart failure,and CHF） in patients with serum Homocysteine（HCY） and high-sensitivity c-reactive protein（HS-CRP） testing,HCY and HS-CRP as CHF risk factors in CHF value of clinical application.Methods On Olympus AU640automatic biochemical analyzer test in the experimen-tal group and the control group of serum samples HCY and HS CRP levels,and the test results are analyzed.Results Experimental group serum Hcy and HS CRP levels are significantly higher than the control group,two groups of comparison,the difference was statistically significant or highly significant（P0.05or P0.01）;CHF patients with single testing at various levels and positive detection rate of joint detection result comparison,the difference was statistically significant（P0.05）.Conclusion Serum HCY and HS CRP concentration detection can be used as a routine CHF risk factors indicators,help improve the positive detection rate of CHF,its concentration level changes in the clinical diagnosis,treatment and prognosis of CHF has certain reference value.
出处
《中国实验诊断学》
2013年第8期1434-1436,共3页
Chinese Journal of Laboratory Diagnosis
