摘要
利用纤维质原料发酵生产燃料酒精是目前研究的热点。综述了五碳糖和六碳糖共发酵生产酒精菌株选育的研究进展。主要介绍了利用自然微生物、重组运动发酵单胞菌(Zymomonas mobilis)、重组大肠杆菌(Escherichia coli)和重组酿酒酵母(Saccharomyces cerevisiae)酒精发酵的进展情况。指出定向进化或改变多个相关基因群,使细胞整体满足木糖的代谢需求,以及对重组菌进行随机突变、进化选育并结合现代高通量筛选等技术是未来研究工作的重点。
The research on fuel ethanol from lignocellulosesis a hot topic.Research progress of strains using pentoses and hexoses in ethanol production was reviewed.Progress of natural microbe,recombinant Zymomonas mobilis,Escherichia coli and Saccharomyces cerevisiae was presented.Direct evolution or changing a number of related gene cluster that make the overall level of the cell to adapt to xylose metabolism,and random mutagenesis and evolutionary engineering of the recombinant strains combining modern high-throughput screening are the focus of future research.
出处
《化工进展》
EI
CAS
CSCD
北大核心
2013年第1期151-155,共5页
Chemical Industry and Engineering Progress
基金
吉林省科技发展重点项目(20120411)
