摘要
目的:了解该院门诊口服降糖药使用情况及发展趋势。方法:以药品销售金额、用药频度(DDDs)为指标,对2010年4月-2013年4月该院门诊就诊糖尿病患者的口服降糖药使用情况进行统计分析,并随机抽取每日门诊处方100张,总共抽取109 500张,然后在该109 500张门诊处方中再一次性随机收集500张诊断为"糖尿病"的处方。通过对患者进行基本体检和回访调查,收集患者性别、年龄、体质量和身高等基本信息,统计该院门诊就诊糖尿病患者年龄、性别和体质量指数(BMI)分布,对不合理用药进行统计分析。结果:2010年4月-2013年4月,该院门诊就诊糖尿病患者使用的口服降糖药销售总金额、总用量及DDDs均呈逐年上升趋势,其中,DDDs持续3年均排前4名的口服降糖药分别为盐酸二甲双胍肠溶胶囊、格列齐特分散片、阿卡波糖胶囊和瑞格列奈片;500张处方中各年龄段患者BMI值均大于25;临床诊断书写不全、处方超用量、遴选的药品不适宜、联合用药不适宜、用法不适宜的不合理率分别为2.6%、5.0%、1.2%、2.0%、3.8%。结论:该院门诊口服降糖药的使用基本合理,但在患者个体化用药方案的建立方面重视程度还不够,临床药学工作与实际临床治疗仍存在很大差距,故该院应进一步加大临床药学工作的开展力度。
OBJECTIVE：To understand the application and development trend of oral hypoglycemic agents in our hospital.METHODS：The application of oral hypoglycemic agents in diabetes mellitus patients from outpatient department of our hospital during Apr.2010-Apr.2013 was analyzed statistically in respects of consumption sum and DDDs.100 outpatient prescriptions were randomly sampled each day;a total of 109 500 prescriptions were collected,among which 500 prescriptions of diabetes mellitus were randomly collected.The basic information of patients was collected in terms of gender,age,weight and height through physical examination and follow-up survey.The distribution of age,gender and BMI in diabetes mellitus patients were analyzed and irrational drug use was also analyzed statistically.RESULTS：From Apr.2010 to Apr.2013,total consumption sum,total amount and DDDs of oral hypoglycemic agents in diabetes mellitus patients showed a rising trend year by year in outpatient department of our hospital.Top 4 oral hypoglycemic agents in the list of DDDs for 3 years were Metformin hydrochloride enteric capsules,Gliclazide dispersible tablet,Acarbose capsules and Repaglinide tablet.BMI of patients in 500 prescriptions were all greater than 25 in average.The proportions of uncompleted writing of clinical diagnosis,over dosage of prescription,unsuitable drug selection,unsuitable drug combination and unsuitable usage were 2.6%,5.0%,1.2%,2.0% and 3.8%.CONCLUSIONS：The use of oral hypoglycemic agents in outpatient department of our hospital is reasonable basically,but it is not enough in the establishment of individualized regimen for patients,so a big gap still exists between clinical pharmacy work and actual clinical treatment.Our hospital should further strengthen the development of clinical pharmacy.
出处
《中国药房》
CAS
CSCD
2013年第34期3183-3185,共3页
China Pharmacy
关键词
口服降糖药
门诊
使用情况
合理用药
临床药学
Oral hypoglycemic agents
Outpatient department
Application
Rational drug use
Clinical pharmacy
