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合并非酒精性脂肪肝的初发2型糖尿病患者胰岛素泵基础率特点

Distribution characteristics of insulin pump basal rate in type 2 diabetic patients with fatty liver
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摘要 目的探讨合并非酒精性脂肪肝的初发2型糖尿病患者胰岛素泵基础率的特点。方法将118例初发2型糖尿病患者分为脂肪肝组(62例)与非脂肪肝组(56例)。分别给予胰岛素泵强化治疗,达到目标血糖后,将基础率分为22:00~3:00,3:00~8:00,8:00~22:00共3段,计算每时段中每小时基础率占全日总基础率的百分比,并进行各时段间比较。结果脂肪肝组中3:00~8:00时段基础率占全日基础率的比例为(5.44±0.38)%,高于非脂肪肝组的(3.58±0.23)%,两组比较差异有统计学意义(P<0.05)。结论 2型糖尿病合并非酒精性脂肪肝患者在黎明时段需要的基础率较非脂肪肝患者高。 Objective To compare the distribution characteristics of insulin pump basal rate in type 2 diabetic patients between fatty liver and non fatty liver. Methods One hundred and eighteen patients of type 2 diabetic were assigned into two groups: fatty liver group and non fatty liver group. All patients were treated with insulin pump. Once the targeted blood glucose level was reached, insulin pump basal rate was observed by 3 parts: 22: 00-3: 00, 3: 00-8: 00, 8: 00±22: 00. Hourly basal rate in average of every part was calculated, whose percentage of the entire day basal rate was compared among different groups. Results 3 : 00 - 8 : 00 basal rate in fatty liver group ( 5.44 ± 0. 38 ) % was higher thanthat of the non fatty liver groups ( 3.58 ± 0. 23 ) % ( P 〈 0. 05 ). Conclusion Insulin pump basal rate is different in two group, and fatty liver group required more basal insulin at daybreak.
作者 肖毅 徐谷根
出处 《新医学》 2013年第8期537-539,共3页 Journal of New Medicine
关键词 胰岛素泵 基础率 2型糖尿病 脂肪肝 Insulin pump Basal rate Diabetes, type 2 Fatty liver
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