摘要
目的：探讨病毒性脑膜炎（病脑），结核性脑膜炎（结脑），化脓性脑膜炎（化脑）患儿脑脊液中ＮＯ含量及临床意义。方法：采用比色法测定病脑（１８例），结脑（９例），化脑（１０例），对照组（１１例）脑脊液中ＮＯ浓度．结果：病脑，化脑，结脑脑脊液中ＮＯ浓度较对照组显著性升高，化脑脑脊液中ＮＯ浓度较病脑，结脑显著升高，差异均有显著意义，（Ｐ＜０．０１）．结论：ＮＯ参与了小儿中枢神经系统感染性疾病的病理生理过程，并可作为化脑诊断及脑膜炎鉴别诊断的客观参考指标。
Objective: To explore the clinical significance of nitric oxide (NO) in cerebrospinal fluid (CSF) in the patients with viral meningitis, tuberculosis meningitis, and purulent meningitis. Method: The CSF NO of 18 cases of viral meningitis, of tuberculosis, 10 of purulent meningitis and 11 of controls were determined by coloimetric method. Result: The NO concentration in patients with viral meningitis, tuberculosis meningitis and purulent meningitis was higher than that in controls. The NO concentration in patients with purulent meningitis was higher than that in patients with viral meningitis and tuberculosis meningitis. There was very obvious difference, P<0.01.Conclusion: NO participates in the pathophysical course in children patients with infection of central nervous system. The determination of NO in CSF has significance to diagnose the dieases of central nervous system infection.
出处
《黑龙江医药科学》
2000年第4期12-13,共2页
Heilongjiang Medicine and Pharmacy
关键词
病毒性脑膜炎
结核性脑膜炎
脑脊液
NO
儿童
viral meningitis
tuberculosis meningitis
purulent meningitis, cerebrospinal fluid
nitric oxide
