摘要
目的 :探讨司帕沙星治疗性病性前列腺炎的有效性和安全性。方法 :75例性病性前列腺炎患者随机分为 A、B两组。 A组 37例口服司帕沙星每天 1次 ,每次 0 .2 g;B组 38例口服氧氟沙星每天 3次 ,每次0 .2 g。两组均连用 2 0 d为一疗程 ,一疗程未愈者继用第二疗程 ,两疗程未愈者停用。结果 :A组患者治愈率86 .5 % ,总有效率 91.9% ;B组患者治愈率 6 5 .8% ,总有效率 73.7%。经统计学处理 ,A组治愈率高于 B组 (χ2=4.40 3,P<0 .0 5 ) ,A组有效率亦高于 B组 (χ2 =4.337,P<0 .0 5 )。结论 :司帕沙星治疗性病性前列腺炎的疗效明显优于氧氟沙星 ,司帕沙星是治疗性病性前列腺炎相对有效和安全的抗菌药物。
To investigate the efficacy and safety of sparfloxacin in the treatment of venereal prostatitis. Seventy five patients were randomized divided into two groups,A group( n=37) was orally given sparfloxacin 0 .2 g once a day;and B group ( n=38) was orally given ofloxacin 0 .2 g three times a day,and the regimen was conducted for2 0 days as one therapeutic course.In case of treatment failure,the regimen was follwed for another course,and then terminated at the end for assessmentof therapy.Results showed thatthe clinical cure rate of two groups were86.5% and 65.8% respectively.The difference was statistically significant( χ2 = 4 .4 4 0 3,P<0 .0 5) .Overall effective rate of two groups were91.9% ,and73.7% respectively( χ2 =4 .337,P< 0 .0 0 5) . It was concluded that the clinical efficacy of sparfloxacin was a superior to ofloxacin and was a safe and effective antibiotic for the treatment of venereal prostatitis.
出处
《中国抗生素杂志》
CAS
CSCD
北大核心
2000年第5期399-400,共2页
Chinese Journal of Antibiotics
关键词
司帕沙星
性病性前列腺炎
安全性
药物治疗
Sparfloxacin
Ofloxacin
Venereal prostatitis
Clinical efficacy
Safety
