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低分子肝素治疗胎儿生长受限对孕妇血栓前状态及新生儿结局的影响 被引量:7

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摘要 目的观察低分子肝素治疗胎儿生长受限(FGR)对孕妇血栓前状态及新生儿结局的影响。方法2010年1月至2012年12月在我院产检发现胎儿生长受限(FGR)患者11例为研究组,正常孕妇11例为对照组,比较研究组低分子肝素治疗前后与对照组孕32周、36周凝血功能及新生儿结局。结果(1)研究组治疗前血小板计数明显低于对照组孕32周,P=0.005,P〈0.05,差异有统计学意义;(2)对照组随孕周增加出现高凝状态,PT逐渐缩短,P=0.023,P〈0.05,差异有统计学意义。(3)研究组治疗后凝血酶原时间(PT)与对照组孕36周比较差异有统计学意义,P=0.036,P〈0.05;(4)两组新生儿出生胎龄无明显差异,P=0.13,P〉0.05;出生体重有明显差异,P=0.022,P〈0.05,但无低体重儿出生。结论胎儿生长受限(FGR)患者存在血栓前状态,低分子肝素治疗可改善FGR患者的血栓前状态及新生儿结局。
出处 《国际医药卫生导报》 2013年第17期2669-2671,共3页 International Medicine and Health Guidance News
基金 2010年江门市科技局科研项目(江科[2010]74)
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