摘要
目的:观察痹康合剂联合甲氨蝶呤和美洛昔康分散片治疗类风湿关节炎临床疗效。方法:将中医辨证属于寒湿痹阻证的类风湿关节炎60例患者随机分为治疗组和对照组,每组30例。对照组给予甲氨蝶呤和美洛昔康分散片治疗,治疗组在对照组治疗基础上加用痹康合剂。观察两组患者治疗前后晨僵时间、关节肿胀数、关节疼痛数、双手握力、红细胞沉降率、C-反应蛋白,并对药物毒副作用进行评分和对比分析。结果:两组患者治疗后症状、体征较治疗前均有显著性改善(P<0.01)。治疗组在晨僵时间、关节肿胀数、关节疼痛数、双手握力、红细胞沉降率和C-反应蛋白等方面改善较对照组明显(P<0.05)。结论:痹康合剂联合甲氨蝶呤和美洛昔康分散片治疗类风湿关节炎疗效确切,其机理可能是在调节人体免疫系统方面发挥作用。
Objective：To observe the clinical effect of treating rheumatoid arthritis rheumatism with bikang mixture combined with methotrexate and meloxicam dispersible tablets.Methods：60 cases with rheumatoid arthritis due to cold dampness were randomly and equally divided into the treatment group and the control group The control group were treated with methotrexate and meloxicam dispersible tablets and the treatment group were given meloxicam dispersible tablets on the basis of the former treatment,observing the morning stiffness time,number of swollen joints,joint pain,hand grip strength,erythrocyte sedimentation rate and C-reactive protein of the two groups before and after treatment and grading and analyzing the drug side effects.Results：The symptoms and signs of the two groups improved after treatment （P 〈 0.01 ） .The treatment group were better than the control group on the aspects of the moming stiffness time,number of swollen joints,joint pain,hand grip strength,erythrocyte sedimentation rate and C-reactive protein （ P 〈 0.05 ） .Conclusion：Bikang mixture combined with methotrexate and meloxicam dispersible tablets had exact curative effect on the treatment of rheumatoid arthritis,whose mechanism might be the regulation of human immune system.
出处
《风湿病与关节炎》
2013年第8期9-11,21,共4页
Rheumatism and Arthritis
关键词
关节炎
类风湿
痹康合剂
甲氨蝶呤
美洛昔康分散片
治疗
arthritis,rheumatoid
bikang mixture
methotrexate
meloxicam dispersible tablets
treatment
