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低氧诱导因子抑制药在抗肿瘤方面的研究进展 被引量:1

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摘要 低氧诱导因子抑制药(YC-1)是一种小分子物质,最初研究主要集中在心血管系统,如抗血小板聚集、收缩血管等方面。研究发现,YC-1能抑制低氧诱导因子-1α(HIF-1α)的表达,从而开启YC-1在抗肿瘤方面的研究。YC-1抗肿瘤作用是多方面的,包括细胞周期抑制和诱导肿瘤细胞凋亡、抗血管生成、抗炎性反应及抑制金属蛋白酶类(MMPs)等。
出处 《医药导报》 CAS 北大核心 2013年第7期915-918,共4页 Herald of Medicine
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参考文献33

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