摘要
Congenital cataract is the main cause of blindness in children, with significantly varying treatment effects. The development of axial length is an important factor that affects the prognosis of these children.However,when compared with the eyes of normal children,the mechanism of growth of the axial length is so complicated that the reported findings differ significantly in terms of the measuring apparatus,assessment methods,and statistical outcome,making the rule of axial length development still unclear. In this paper, we first review the process of axial length development in normal healthy children and compare different hypotheses about certain factors that could affect the development of axial length. The results of some current research about the characteristics of axial length development in congenital cataract children are then reviewed. Lastly, the advantages and disadvantages of current axial length measurements methods are compared and analyzed.The purpose of this review is to improve our understanding of the complexity and importance of axial length development and to suggest better use of axial length monitoring measurements in congenital cataract children for pediatric ophthalmologists,with the hope of offering assistance that will enhance long-term therapeutic effects for these children.
Congenital cataract is the main cause of blindness in chil- dren, with significantly varying treatment effects. The development of axial length is an important factor that affects the prognosis of these children. However, when compared with the eyes of normal children, the mechanism of growth of the axial length is so complicated that the reported findings differ significantly in terms of the measuring apparatus, assessment methods, and statistical outcome, making the rule of axial length development still unclear. In this paper, we first review the process of axial length development in normal healthy children and compare different hypotheses about certain fac- tors that could affect the development of axial length. The re- sults of some current research about the characteristics of axial length development in congenital cataract children are then reviewed. Lastly, the advantages and disadvantages of current axial length measurements methods are compared and ana- lyzed. The purpose of this review is to improve our under- standing of the complexity and importance of axial length de- velopment and to suggest better use of axial length monitoring measurements in congenital cataract children for pediatric ophthalmologists, with the hope of offering assistance that will enhance long-term therapeutic effects for these children.
基金
Key Program for Clinical Discipline of Ministry of Health between 2010 and 2012(Grant No.2010-2012-439-175)
