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雷公藤多甙联合中小剂量泼尼松治疗老年原发性肾病综合征临床研究 被引量:5

Clinical Study of Tripterygium Glycosides Combined with Small Dose of Prednisone in the Treatment of Elderly Patients with Primary Nephrotic Syndrome
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摘要 目的:探讨雷公藤多甙联合中小剂量泼尼松治疗老年原发性肾病综合征的临床疗效。方法:采用雷公藤多甙联合中小剂量泼尼松治疗老年原发性肾病综合征患者36例(研究组),并与单独采用泼尼松治疗的36例老年原发性肾病综合征患者(对照组)进行临床疗效和不良反应比较。结果:研究组总缓解率为91.67%,对照组总缓解率为72.22%,研究组的完全缓解率和总缓解率均明显高于对照组,差异具有统计学意义(P<0.05);研究组的不良反应发生率(13.89%)明显低于对照组(47.22%),差异具有统计学意义(P<0.05)。结论:雷公藤多甙联合中小剂量泼尼松治疗老年原发性肾病综合征的临床疗效优于单纯应用用泼尼松治疗,且不良反应少,值得临床推广使用。 Objective:To investigate the joint TWP small dose prednisone therapy in elderly patients with primary nephrotic syndrome clinical efficacy.Methods:TWP small dose prednisone joint research group of elderly patients with primary nephrotic syndrome in 36 cases,and with the use of prednisone alone control group of 36 cases of elderly patients with primary nephrotic syndrome clinical Comparative efficacy and adverse reactions.Results:The total response rate was 91.67% in the control group,the total response rate was 72.22%,the study group's complete remission rate and overall response rate was significantly higher,the difference was statistically significant(P〈0.05);study group the incidence of adverse reactions(13.89%) was significantly lower than the control group(47.22%),and the difference was statistically significant(P〈0.05).Conclusion:TWP joint small dose prednisone treatment of elderly nephrotic syndrome more effective than treatment with prednisone alone applications and fewer adverse reactions,worthy of clinical use.
作者 鲍宇
出处 《亚太传统医药》 2013年第7期172-173,共2页 Asia-Pacific Traditional Medicine
关键词 雷公藤多甙 泼尼松 老年原发性肾病综合征 TWP Prednisone Elderly Patients With Primary Nephrotic Syndrome
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