摘要
目的:探讨中西医结合治疗中晚期胃癌的临床疗效。方法:将120例中晚期胃癌患者按随机数字表法分为对照组和观察组,两组均给予化疗、营养支持、纠正水和电解质酸碱平衡、止呕等常规治疗;治疗组加用健脾祛瘀化痰法治疗,方药组成:党参、灸黄芪、八月扎各15 g,焦白术、丹参各12 g,莪术、灵芝、陈皮、生甘草各10 g,白花蛇舌草、生薏苡仁、怀山药各30 g,30 d为1个疗程,观察两组有效率、生活质量、临床症状、不良反应。结果:观察组有效率为53.33%,生活质量提高53.33%,临床症状改善率为80.00%;对照组有效率为43.33%,生活质量提高30.00%,临床症状改善率为60.00%,两组比较差异均有统计学意义(P<0.05),两组不良发应比较,差异有统计学意义(P<0.05)。结论:中西医结合治疗中晚期胃癌疗效确切,可以改善患者生活质量和临床症状,减少化疗的不良反应。
Objective：To explore the clinical curative effect of combined traditional Chinese and western medicine treatment of middle and advanced gastric cancer.Methods：120 patients with middle and advanced gastric cancer were randomly divided into the control group and the observation group.Two groups were given conventional treatment such as chemotherapy,nutritional support,correcting water,electrolyte and acid base balance,anti-nausea and so on.The treatment group was additionally treated with strengthening spleen,dispelling blood stasis and reducing phlegm method,composition：codonopsis pilosula 15 g,radix astragali preparata15 g,akebiae fructus15 g,roasted atractylodis macrocephala 12 g,salviae miltiorrhizae 12 g,curcuma zedoary 10 g,lucid ganoderma 10 g,pericarpium citri reticulatae 10 g,origin liquorice 10 g,oldenlandia diffusa 30 g,raw semen coicis 30 g,rhizome dioscorea 30 g.A dose one day,decoction with water and taking decoction for twice.30 days for a course of treatment.Effective rate,quality of life,clinical symptoms and adverse reactions of the two groups were observed.Results：In the observation group,the effective rate was 53.33%,quality of life was increased by 53.33%,and clinical symptoms improvement rate was 80.00%.In the control group,the effective rate was 43.33%,quality of life was increased by 30.00%,and clinical symptoms improvement rate was 60.00%.Comparison those of the two groups showed that the differences were statistically significant（P0.05）.Comparison of adverse reaction of the two groups showed that the difference was statistical significance（P0.05）.Conclusion：Combination of traditional Chinese and western medicine treatment of locally middle and advanced gastric cancer has definitely curative effect,which can improve the patients′ quality of life and clinical symptoms,and reduce the adverse reaction of chemotherapy.
出处
《中医学报》
CAS
2013年第8期1104-1105,共2页
Acta Chinese Medicine
基金
广西自然科学基金项目(编号:2012GXNSFFA0300008)
关键词
中晚期胃癌
中西医结合治疗
健脾祛瘀化痰法
生活质量
advanced gastric cancer
combination of traditional Chinese and western medicine treatment
strengthening spleen
dispelling blood stasis and reducing phlegm method
quality of life
