摘要
目的 :为降低院内感染的发生率 ,合理用药 ,对内科住院病人院内感染和抗性素应用之间关系作一探讨 ,以便合理使用抗生素。方法 :对 1996年～ 1997年内科 96 0份住院病历院内感染及抗生素使用情况进行了回顾性分析。结果 :(1)本组院内感染率 8.1% ,抗生素使用率 86 .3%。预防性应用抗生素是治疗性应用 1.4倍 ,依据病原菌培养及药敏用药仅占 13.5 %。 (2 )应用广谱抗生素占 6 5 .9% ,联合用药占 5 8.8% ,疗程 >2 1天占 2 2 .2 %。预防用药院内感染率 10 .7% ,盲目用药 14.9% ,应用广谱抗生素10 .6 % ,使用 3种抗生素 2 3.9% ,疗程 >2 1天 17.9%。结论 :不合理应用抗生素 ,必然产生细菌耐药和导致菌群失调 ,增加院内感染率。做好病房消毒隔离 ,控制预防性使用抗生素 ,根据病情病原菌及药敏合理使用抗生素至为重要。
Objective:In order to reduce the incidence of the nosocom ial infections and rational application of antibiotic.To explore the relationship between the nosocom ial infections inpatients of internal medicine and antibiotic's application.Methods:The state of nosocomial infections and antibiotic's application which were 96 0 m edical records from 1996 to 1997were m ade analyzed retrospectively.Results:1.The rate of nosocpm ial infection in this group was 8.1% .The rate of antibiotic's application was86 .3% .The preventive application was1.4tim es application for curing the antibiotic's application according to the culturing of pathogen and test of drug sensitivity was13.5 % .2 . The aplication of broad- spectrum s6 5 .1% united application was5 8.8% course of treatment more than 2 1days was2 2 .2 % .The rate of nosocom ial infections in preventive application was10 .7% ,blind application was 14.9% .The application of broad- spectrum was 10 .6 % ,application three kinds of antibiotic at same tim e was17.9% .Conclusions:Unreasonable application in antibiotic must result in drug- resisting and bacterium im balance and the rate of nosocom ial infections increasing.It's very im portant to sterilize and isolate wards,control the preventive application antibiotics and applicant rationally the antibiotics according to the disease and the test of drug sensitivity. [
出处
《中国民政医学杂志》
2000年第5期284-286,共3页
Medical Journal of Chinese Civil Administration
