摘要
目的:探讨入院时肝肾功能与NT-proBNP水平对扩张型心肌病患者预后的影响。方法:114例扩张型心肌病患者为四组,分别是扩张型心肌病伴肝肾功能不全组(A组)26例,伴肝功能不全组(B组)16例,伴肾功能不全组(C组)28例和肝肾功能正常组(D组)44例。首次入院后检测肝肾功能和血浆NT-proBNP浓度;所有患者随访并记录1年内发生的主要不良心血管事件(MACE)。结果:A组患者NT-proBNP水平、恶性心律失常发生率和总死亡率较其他三组均较显著升高(P<0.05);D组患者MACE发生率在四组中最低(P<0.05)。结论:肝肾功能与NT-proBNP可以很好的评估扩张型心肌病患者的预后,指导临床治疗。
Objective：To investigate the effects of liver and kidney function and NT-proBNPlevel on patients with dilated cardiomyopathy.Methods：114 patients with dilated cardiomyopathy were divided into four groups,including dilated cardiomyopathy associated with liver and kidney dysfunction group（group A,n=26）,associated with liver dysfunction group（group B,n=16）,associated with kidney dysfunction group（group C,n=26） and normal liver and kidney function group（group D,n=26）.Liver and kidney function and plasma NT-proBNP concentration were detected after first time adminssion.All patients were followed up and recorded major adverse cardiac events（MACE）occurred in one year.Results：The NTproBNP level,incidence of malignant arrhythmias and total mortality in groupA were significantly higher than other three groups（P0.05）.The incidence of MACE in group D was lowest in the four groups（P0.05）.Conclusion：Liver and kidney function and NT-proBNP can better assess the prognosis of patients with dilated cardiomyopathy and guide Clinical treatment.
出处
《中国医药导刊》
2013年第6期930-931,共2页
Chinese Journal of Medicinal Guide
