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急性心肌梗死患者超敏C反应蛋白和N末端-脑钠肽前体的临床观察

Clinical Observation of High Sensitivity C-reactive Protein and N-terminal Pro-brain Natriuretic Peptide in Patients with Acute Myocardial Infarction
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摘要 目的:探讨急性心肌梗死(AMI)患者急性期超敏C反应蛋白(hs-CRP)和N-末端脑钠肽前体(NTproBNP)水平及其临床意义。方法:将AMI患者76例分为ST段抬高急性心肌梗死(STEMI组,n=53)和非ST段抬高急性心肌梗死(NSTEMI组,n=23),并以健康者对照(C组,n=20),就诊时立即检测血浆hs-CRP浓度和NTproBNP水平。结果:STEMI组血浆hs-CRP、NT-proBNP均显著高于NSTEMI组和对照组(P<0.01)。结论:AMI患者血浆hs-CRP和NT-proBNP水平在急性期显著升高,并与心肌缺血的严重程度相关。 Objective: To explore the levels and clinical significance of high sensitivity C-reactive protein (hs- CRP) and plasma N-terminal pro-brain natriuretic peptide (NT-proBNP) in patients with acute myocardial infarction (AMI). Methods: 76 patients with AMI were divided into STEMI group(n=53) and NSTEMI group(n=23), while healthy adult as control group(n=20), hs-CRP and NT-proBNP were measured immediately after the patients with AMI arriving the emergency room. Results: Compared with the control group and NSTEMI group,plasma hs-CRP, NT- proBNP significantly increased in STEMI group (P〈0.01). Conclusion: The hs-CRP and NT-proBNP elevated on the early stage in patients with AMI, and had a positive correlation to the degree of the myocardial ischemia.
出处 《岭南急诊医学杂志》 2013年第4期259-260,263,共3页 Lingnan Journal of Emergency Medicine
关键词 急性心肌梗死 超敏C反应蛋白 N-末端脑钠肽前体 acute myocardial infarction high-sensitivity C-reactive protein N-terminal pro-brain natriuretie peptide
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