摘要
目的 探讨内皮素-1(ET-1)在脑出血、脑梗死和蛛网膜下腔出血中的作用.方法 实验测定82例脑卒中病人(实验组)和30例健康人(对照组)的血清内皮素-1浓度.结果 蛛网膜下腔出血组(SAH组)内皮素的浓度为(37.18±5.26)pg/ml,脑梗死组为(24.21±5.58)pg/ml,脑出血组为(27.06±6.54)pg/ml,健康对照组为(3.13±4.67)pg/ml.实验组较对照组有显著性差异.结论 脑卒中病人血ET-1明显升高,应用ET-1对抗药能有效预防和治疗脑卒中.
ve To study the effect of ET-1 on cerebral hemorrhage, cerebral infarction and SAH.Methods The concentrations of ET-1 were determined experimentally for 82 cases of cerebral vessel diseases as testgroup and 30 healthy subjects as control group. Results ET-1 level was (37. 18 ± 5. 26)pg/ml in SAH group, (24. 21 ±5. 58) pg/ml in cerebral infarction group, (27. 06 ± 6. 54) pg/ml in cerebral hemorrhage group, (3. 13 ± 4. 67) pg/ml inhealthy group. The significant difference was found in test group comparing with control group. Conclusions Theconcentration of ET-1 of cerebral stroke patient was much higher than that of normal subject. The application of an-ti-ET-1 medicine can effectively prevent and treat cerebral stroke.
关键词
内皮素-1
蛛网膜下腔出血
脑梗死
脑出血
ET-1
Subarachnoid hemorrhage
Cerebral infarction
Cerebral hemorrhage
