摘要
目的探讨静脉注射丙种球蛋白(IVIG)对手足口病并神经损害患儿的临床疗效。方法选择68例手足口病合并神经系统损害的患儿,随机分为等量的实验组和对照组,均给予相同的抗病毒和对症基础治疗,在此基础上,实验组每天给予静脉注射小剂量(0.4g/kg)IVIG;对照组给予羚羊角治疗,观察两组患儿神经症状的平均好转时间、发热缓解时间及其痊愈时间、危重病的发生率。结果 IVIG治疗组患儿的神经系统好转时间、发热缓解时间和痊愈时间均短于对照组,且危重病发生率低,两组比较差异有统计学意义(P<0.05)。结论应用静脉注射IVIG治疗小儿手足口病疗效显著,值得临床推广使用。
Objective To investigate the clinical efficacy of intravenous injection gamma globulin in hand,foot and mouth disease patients with nerve damage. Methods 68 cases of patients with hand,foot and mouth disease associated with nervous system damage in children,were randomly divided into the same amount of experimental and control groups,both given the same basis of anti-virus and symptomatic treatment,on this basis,the experimental group were given small doses of intravenous injection gamma globulin （IVIG） （0.4 g/kg）;The control group were given antelope horn~＇Average treatment improvement time was observed in patients with neurological symptoms,and recorded the fever duration time of remission,recovery time,the incidence of critical illness. Results Children with IVIG treatment group compared with the control group,the time of the improvement of the nervous system,fever relief and heal time was short,the incidence of critical illness was low,the two groups was statistically significant （P〈0.05）. Conclusion Intra- venous immunoglobulin has a significant effect on the treatment of children with hand,foot and mouth disease,and it is worthy of clinical use.
出处
《中国当代医药》
2013年第22期74-75,共2页
China Modern Medicine
关键词
手足口病
神经系统损害
丙种球蛋白
Hand,foot and mouth disease
Nervous system damage
Gamma globulin
