摘要
目的:比较不同病理分期膀胱癌组织标本中netrin-1表达量的差异,分析其表达量与膀胱癌临床分期的关系。方法:选取膀胱癌组织标本100例,免疫组化方法检测netrin-1表达量。结果:netrin-1在膀胱癌组织中随病理分期的升高,表达量增加(P<0.05)。结论:netrin-1表达量与膀胱癌临床病理分期显著相关,对推测膀胱癌的术前分期以及对临床选择治疗方案和估计预后具有重要意义。
Objective：Comparing the different expressions of netrin-1 in different pathological staging of bladder cancer tissue slices and analyze the relationship between bladder cancer in different clinical stages of pathologic parameters.Methods：Selected 100 cases of clinical bladder cancer tissue,detected the expression of netrin-1 by immunohistochemistry.Results：The expressions of netrin-1 in bladder cancer tissue sections increased with the pathological stage increased（P 0.05）.Conclusion：Netrin-1 expression level is significantly related to the clinical pathological staging of bladder cancer.It can speculate the clinical pathological staging of bladder cancer,help to choose clinical treatment and estimate prognosis.
出处
《现代肿瘤医学》
CAS
2013年第8期1792-1795,共4页
Journal of Modern Oncology
基金
国家自然科学基金项目(编号:81172438)
