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纳洛酮联合醒脑静治疗急性重度酒精中毒临床疗效分析 被引量:21

Analysis of Naloxone Combined with Xingnaojing in Treatment of Acute Severe Alcoholism
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摘要 目的探讨纳洛酮联合醒脑静治疗急性重度酒精中毒的临床疗效。方法将116例急性重度酒精中毒患者随机分为对照组(56例)和观察组(60例),两组患者均接受常规治疗,同时给予对照组患者醒脑静治疗,观察组患者接受纳洛酮联合醒脑静治疗。比较两组的临床疗效及患者苏醒后临床症状。结果观察组治疗有效率显著高于对照组(88.3%vs 69.6%)(P<0.05);观察组患者清醒时间、症状缓解时间及出院时间显著早于对照组(P<0.05);观察组患者苏醒后头痛、头晕、恶心、呕吐等临床症状发生率显著低于对照组(P<0.05)。结论纳洛酮联合醒脑静治疗急性重度酒精中毒具有协同作用,疗效更为理想。 Objective To explore the clinical effect of naloxone combined with xingnaojing in treatment of acute severe alcoholism.Methods One hundred and sixteen cases with acute severe alcoholism were randomly divided into control group(56 cases) and observation group(60 cases).Both of the groups received routine treatment,and the control group was given xingnaojing treatment,while the observation group received naloxone combined with xingnaojing treatment.Clinical effect and the symptoms after recovery were compared between the two groups.Results Effective rate of treatment of the observation group was much higher than the control group(88.3% vs 69.6%,P 0.05);The awake time,symptoms relief time and hospital discharge of the observation group were much earlier than the control group(P 0.05);the symptoms after recovery including dizzy,headache,nausea and vomiting of the observation group were much lower than the control group(P 0.05).Conclusion Naloxone combined with xingnaojing have synergistic effect on acute severe alcoholism,with more ideal effects.
作者 孙云飞
出处 《医学综述》 2013年第15期2856-2857,共2页 Medical Recapitulate
关键词 酒精中毒 纳洛酮 醒脑静 Alcoholism Naloxone Xingnaojing
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